Menadiol diacetate synthesis
- Product Name:Menadiol diacetate
- CAS Number:573-20-6
- Molecular formula:C15H14O4
- Molecular Weight:258.27
481-85-6
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573-20-6
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Yield:573-20-6 90.2 %
Reaction Conditions:
with pyridine at 65 - 70;
Steps:
1.2; 2; 3.2
(2) the above0.45 g (0.006 mol) of pyridine is added to the 2-methyl-1,4-naphthalenediol ethyl acetate solution,17.1 g (0.167 mol) of acetic anhydride was added dropwise at 65-70° C. and aged at the same temperature for 3 hours. The organic layer was washed with city water and 5% sodium bicarbonate water,The organic layer was concentrated, and a mixed solution of isopropanol (IPA) and city water was added to the residue. The resulting slurry was filtered and dried under reduced pressure to give 12.0 g of colorless crystalline powder of 1,4-diacetoxy-2-methylnaphthalene.(0.046 mol) was obtained.HPLC purity is 99.96 Area%,The yield from bisulfite trihydrate of 2-methylnaphthoquinone was 90.2%.
References:
JP2023/16443,2023,A Location in patent:Paragraph 0023-0025
58-27-5
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$14.00/250ML
573-20-6
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$25.00/10g
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64-19-7
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573-20-6
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67-56-1
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573-20-6
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58-27-5
523 suppliers
$5.00/250mg
573-20-6
223 suppliers
$25.00/10g