Methyl 1-Boc-5-oxopyrrolidine-2-carboxylate synthesis
- Product Name:Methyl 1-Boc-5-oxopyrrolidine-2-carboxylate
- CAS Number:861657-91-2
- Molecular formula:C11H17NO5
- Molecular Weight:243.26
67-56-1
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$9.00/25ml
24424-99-5
863 suppliers
$13.50/25G
149-87-1
333 suppliers
$6.00/25g
861657-91-2
26 suppliers
$91.67/1g
Yield:861657-91-2 70%
Reaction Conditions:
Stage #1: methanol;Pyroglutamic acidwith thionyl chloride at 20 - 25; for 1 h;
Stage #2: di-tert-butyl dicarbonatewith dmap in ethyl acetate at 20 - 25; for 3 h;
References:
Hall, Christopher J. J.;Goundry, William R. F.;Donohoe, Timothy J. [Angewandte Chemie - International Edition,2021,vol. 60,# 13,p. 6981 - 6985][Angew. Chem.,2021,vol. 133,# 13,p. 7057 - 7061,5] Location in patent:supporting information
24424-99-5
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$13.50/25G
4931-66-2
284 suppliers
$10.00/5g
861657-91-2
26 suppliers
$91.67/1g
145681-01-2
74 suppliers
$25.00/1g
861657-91-2
26 suppliers
$91.67/1g
149-87-1
333 suppliers
$6.00/25g
861657-91-2
26 suppliers
$91.67/1g