METHYL 3,5-DIMETHYLBENZOATE synthesis
- Product Name:METHYL 3,5-DIMETHYLBENZOATE
- CAS Number:25081-39-4
- Molecular formula:C10H12O2
- Molecular Weight:164.2
499-06-9
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$6.00/10g
25081-39-4
112 suppliers
$6.00/250mg
Yield: 90%
Reaction Conditions:
with sulfuric acid in methanol
Steps:
1 Preparation of methyl-3,5-dimethyl-benzoate
Example 1 Preparation of methyl-3,5-dimethyl-benzoate A solution of 3,5-dimethyl benzoic acid (25 g, 0.17 mol) in methanol (250 ml) was treated with sulfuric acid (1 ml, cat. amount) and heated to reflux. After 10 hours, the solution was cooled to room temperature, concentrated to approximately 1/2 volume and poured into 200 ml of crushed ice. The mixture was extracted twice with 200 ml portions of diethyl ether. The organic phase was extracted with saturated aqueous sodium carbonate, dried over magnesium sulfate, and concentrated under reduced pressure. The resulting solid was recrystallized from hexanes to yield the product (24.5 g, 90% yield) as volatile white plates. mp=32°-35° C. (lit. mp=35°-36° C.)
References:
The Trustees of Columbia University in the City of New York US5342934, 1994, A
499-06-9
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$6.00/10g
67-56-1
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25081-39-4
112 suppliers
$6.00/250mg
929626-17-5
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$80.00/500mg
74-88-4
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$15.00/10g
25081-39-4
112 suppliers
$6.00/250mg
67-56-1
776 suppliers
$7.29/5ml-f
5779-95-3
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$15.00/1g
25081-39-4
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$6.00/250mg
4919-37-3
135 suppliers
$23.00/1g
25081-39-4
112 suppliers
$6.00/250mg