MFCD04222117 synthesis
- Product Name:MFCD04222117
- CAS Number:99584-32-4
- Molecular formula:C8H8N4O
- Molecular Weight:176.18
90-04-0
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122-51-0
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99584-32-4
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$240.00/0.500g
Yield:99584-32-4 89%
Reaction Conditions:
with sodium azide in water at 70; for 1.2 h;
Steps:
2.4 General procedure for the synthesis of 1-substituted-1H-tetrazoles derivatives in the presence of a catalytic amount of the [AMWCNTs-O-Cu(II)-PhTPY]
General procedure: Amine (1.0mmol), HC(OEt)3 (1.0mmol) and NaN3 (1.3mmol) were mixed and stirred in water (2mL) in the presence of 4mol-% of [AMWCNTs-O-Cu(II)-PhTPY] at 70°C in an uncapped vial. After the completion of the reaction, as monitored by TLC using n-hexane/ethyl acetate, the mixture was diluted by H2O (5mL), then the mixture was vacuum-filtered onto a sintered-glass funnel, and the residue was consecutively washed with ethyl acetate (30mL), water (5mL). The combined supernatant and organic washings were extracted with ethyl acetate (3×10mL), the combined organic layer was dried over anhydrous Na2SO4. Removal of the solvent under vacuum, followed by purification on silica gel using hexane/ethyl acetate as the eluent afforded the pure products.
References:
Sharghi, Hashem;Ebrahimpourmoghaddam, Sakineh;Doroodmand, Mohammad Mahdi [Journal of Organometallic Chemistry,2013,vol. 738,p. 41 - 48]
135-02-4
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99584-32-4
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$240.00/0.500g
20771-60-2
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99584-32-4
6 suppliers
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90-04-0
353 suppliers
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149-73-5
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$12.00/5g
99584-32-4
6 suppliers
$240.00/0.500g