N-Desbenzyl N-tert-butyloxycarbonyl Donepezil synthesis

5synthesis methods

Product Name:N-Desbenzyl N-tert-butyloxycarbonyl Donepezil
CAS Number:948550-60-5
Molecular formula:C22H31NO5
Molecular Weight:389.49

1-Piperidinecarboxylic acid, 4-[(1,3-dihydro-5,6-dimethoxy-1-oxo-2H-inden-2-ylidene)methyl]-, 1,1-dimethylethyl ester

1020717-67-2
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N-Desbenzyl N-tert-butyloxycarbonyl Donepezil

948550-60-5
10 suppliers
$174.90/5mg

Yield:948550-60-5 30%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium⁽⁰⁾;diphenylsilane;zinc(II) chloride in chloroform at 20; for 24 h;

References:

Renou, Julien;Dias, José;Mercey, Guillaume;Verdelet, Tristan;Rousseau, Catherine;Gastellier, Anne-Julie;Arboléas, Mélanie;Touvrey-Loiodice, Mélanie;Baati, Rachid;Jean, Ludovic;Nachon, Florian;Renard, Pierre-Yves [RSC Advances,2016,vol. 6,# 22,p. 17929 - 17940]

6457-49-4 Synthesis