ChemicalBook CAS DataBase List O-Mesitylenesulfonylhydroxylamine

O-Mesitylenesulfonylhydroxylamine synthesis

5synthesis methods

Product Name:O-Mesitylenesulfonylhydroxylamine
CAS Number:36016-40-7
Molecular formula:C9H13NO3S
Molecular Weight:215.27

36016-39-4 Synthesis

tert-Butyl (Mesitylsulfonyl)oxycarbaMate

36016-39-4
91 suppliers
$19.00/250mg

36016-40-7
123 suppliers
inquiry

Yield:36016-40-7 100%

Reaction Conditions:

with trifluoroacetic acid at 0; for 1.5 h;

Steps:

Amino 2,4,6-trimethylbenzenesulfonate

TFA (10 mL) was cooled to ice temperature, then Intermediate] (5.0 g, 15.87 mmol) was added. The reaction mixture was stirred at 0°C for 1.5 h, then poured onto crushed ice. The resulting white-coloured precipitate was filtered off, then washed with water (100 mL) and dried under vacuum, to obtain the title compound (4.1 g, quantitative) as a white solid. This material was taken though to the next step without any purification.0H (400 MHz, CDC13) 6.99 (s, 2H), 5.48 (s, 2H), 2.68 (s, 6H), 2.32 (s, 3H).

References:

WO2015/86502,2015,A1 Location in patent:Page/Page column 81

38202-27-6 Synthesis