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p-Tolyl phosphorodichloridate synthesis

3synthesis methods
-

Yield:878-17-1 89%

Reaction Conditions:

with triethylamine;trichlorophosphate in diethyl ether;1.) from 0 deg C to RT, 15 h, 2.) reflux, 2h;

References:

McGuigan;Pathirana;Balzarini;De Clercq [Journal of Medicinal Chemistry,1993,vol. 36,# 8,p. 1048 - 1052]