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P-TOLYLAMINO-ACETIC ACID synthesis

10synthesis methods
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Yield:21911-69-3 95%

Reaction Conditions:

Stage #1: p-toluidine;ethyl bromoacetatewith potassium carbonate for 1.5 h;Milling;
Stage #2: with potassium hydroxide for 1.5 h;Milling;

References:

Pétry, Nicolas;Vanderbeeken, Thibaut;Malher, Astrid;Bringer, Yoan;Retailleau, Pascal;Bantreil, Xavier;Lamaty, Frédéric [Chemical Communications,2019,vol. 55,# 64,p. 9495 - 9498] Location in patent:supporting information