PIPERIDIN-1-YL-ACETIC ACID synthesis
- Product Name:PIPERIDIN-1-YL-ACETIC ACID
- CAS Number:3235-67-4
- Molecular formula:C7H13NO2
- Molecular Weight:143.18
23853-10-3
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3235-67-4
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Yield: 95%
Reaction Conditions:
with hydrogenchloride in water at 95; for 16 h;
Steps:
21.b b) 2-(Piperidin-l-yl) acetic acid
b) 2-(Piperidin-l-yl) acetic acidThe solution of ethyl 2-(piperidin-l-yl)acetate (1 g, 5.84 mmol, 1.0 eq) in 8 N HC1 was stirred at 95 °C for 16 h. The mixture was concentrated and quenched and extracted as in Intermediate Example 15(b). The solvent was distilled off to afford the product in 95 % yield (0.8 g). LC-MS (ESI): Calculated mass: 143.1 ; Observed mass 144.4 [M+H] + (rt: 0.21 min).
References:
ORION CORPORATION;LINNANEN, Tero;WOHLFAHRT, Gerd;NANDURI, Srinivas;UJJINAMATADA, Ravi;RAJAGOPALAN, Srinivasan;MUKHERJEE, Subhendu WO2013/53983, 2013, A1 Location in patent:Page/Page column 41
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4847-93-2
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110-89-4
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3235-67-4
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