ChemicalBook CAS DataBase List Piperonyl acetone

Piperonyl acetone synthesis

7synthesis methods

Product Name:Piperonyl acetone
CAS Number:55418-52-5
Molecular formula:C11H12O3
Molecular Weight:192.21

By condensation of heliotropin with acetone, followed by hydrogenation in the presence of a palladium catalyst

139-85-5
797 suppliers
$5.00/1g

55418-52-5
124 suppliers
$10.00/5g

Yield:-

Steps:

Multi-step reaction with 3 steps
1: caesium carbonate / N,N-dimethyl-formamide / 2 h / 110 °C
2: sodium hydroxide / water / 0 - 20 °C
3: palladium 10% on activated carbon; hydrogen / methanol / 3 h / 1551.49 Torr

References:

Dhuru, Sameer;Bhedi, Dilip;Gophane, Dnyaneshwar;Hirbhagat, Kiran;Nadar, Vijaya;More, Dattatray;Parikh, Sapna;Dalal, Roda;Fonseca, Lyle C.;Kharas, Firuza;Vadnal, Prashant Y.;Vishwakarma, Ram A.;Sivaramakrishnan [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 12,p. 3784 - 3787]