prenylamine synthesis
1synthesis methods
- Product Name:prenylamine
- CAS Number:390-64-7
- Molecular formula:C24H27N
- Molecular Weight:329.4779
Yield:390-64-7 80%
Reaction Conditions:
Stage #1:1-phenylpropadiene;3-diphenylpropyl amine with tris(dimethylamido)(trityl(6-(tritylamino)pyridin-2-yl)amido)-titanium in toluene at 80; for 24 h;Schlenk technique;Inert atmosphere;
Stage #2: with sodium cyanoborohydride;zinc(II) chloride in methanol at 25; for 20 h;Schlenk technique;Inert atmosphere;regioselective reaction;
References:
Lühning, Lars H.;Brahms, Christian;Nimoth, Jelte P.;Schmidtmann, Marc;Doye, Sven [Zeitschrift fur Anorganische und Allgemeine Chemie,2015,vol. 641,# 12-13,p. 2071 - 2082]