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ChemicalBook CAS DataBase List Prodiamine
29091-21-2

Prodiamine synthesis

2synthesis methods
A method for the preparation of Prodiamine. It includes the following steps: 1) adding 2,4-dichloro-3,5-dinitrobenzotrifluoride and water in a reactor, adding di-n-propylamine and an inorganic base dropwise under heating and stirring, holding the reaction
-

Yield: 0.345 g

Reaction Conditions:

with ammonia in 1,4-dioxane at 95 - 100; for 40 h;Sealed flask;

References:

Endeshaw, Molla M.;Li, Catherine;Leon, Jessica De;Yao, Ni;Latibeaudiere, Kirk;Premalatha, Kokku;Morrissette, Naomi;Werbovetz, Karl A. [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 17,p. 5179 - 5183] Location in patent:supporting information; experimental part

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