PYRAZINE-2-CARBOXIMIDIC ACID METHYLESTER synthesis
- Product Name:PYRAZINE-2-CARBOXIMIDIC ACID METHYLESTER
- CAS Number:74617-55-3
- Molecular formula:C6H7N3O
- Molecular Weight:137.14
67-56-1
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$9.00/25ml
19847-12-2
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$6.00/5g
74617-55-3
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$60.00/10mg
Yield:74617-55-3 82%
Reaction Conditions:
with 1,8-diazabicyclo[5.4.0]undec-7-ene for 1 h;Reflux;
Steps:
3.2.1. Synthesis of Methyl Pyrazine-2-Carbimidate
First, 11 mL (0.12 mol) of cyanopyrazine was dissolved in 30 mL of MeOH, and 0.5mL (3.3 mmol) of DBU (1,8-diazabicyclo [5.4.0]undec-7-ene) was added. The mixture was refluxed for 1 h and cooled, and the carbimidate precipitate was filtered off. Thus, 13.5 g(82%) of the product was obtained. Carbimidate was recrystallized from methanol. Analytical data were in accordance with the literature [29,30].
References:
Climova, Alina;Pivovarova, Ekaterina;Rogalewicz, Bart?omiej;Raducka, Anita;Szczesio, Ma?gorzata;Korona-G?owniak, Izabela;Korga-Plewko, Agnieszka;Iwan, Magdalena;Gobis, Katarzyna;Czylkowska, Agnieszka [Molecules,2022,vol. 27,# 11,art. no. 3467]
19847-12-2
363 suppliers
$6.00/5g
124-41-4
729 suppliers
$12.00/25g
74617-55-3
19 suppliers
$60.00/10mg
19847-12-2
363 suppliers
$6.00/5g
74617-55-3
19 suppliers
$60.00/10mg