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ChemicalBook CAS DataBase List (R)-1-[2-(Trifluoromethyl)phenyl]ethylamine
127733-46-4

(R)-1-[2-(Trifluoromethyl)phenyl]ethylamine synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium acetate hydrate / ethanol; H2O / 20 h / Heating
2: borane, (S)-2-amino-3-methyl-1,1-diphenyl-1-butanol <(S)-3> / tetrahydrofuran

References:

Pickard, Simeon T.;Smith, Howard E. [Journal of the American Chemical Society,1990,vol. 112,# 15,p. 5741 - 5747]

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