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ChemicalBook CAS DataBase List (R)-1-(3-Bromophenyl)ethylamine

(R)-1-(3-Bromophenyl)ethylamine synthesis

4synthesis methods
2142-63-4 Synthesis
3'-Bromoacetophenone

2142-63-4
385 suppliers
$5.00/10g

-

Yield:-

Steps:

Multi-step reaction with 5 steps
1.1: bromine / dichloromethane / 1 h / 0 °C
2.1: hydroxylamine hydrochloride / water; methanol / 25 °C
3.1: sodium tetrahydroborate / water; acetonitrile / 0.17 h / 25 °C
4.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C
4.2: 18 h / 20 °C
5.1: C19H23BNO3(1-)*H(1+); borane-THF / 1,4-dioxane; tetrahydrofuran / 0 °C / Inert atmosphere

References:

Ou, Wenhua;Espinosa, Sandraliz;Melendez, Hector J.;Farre, Silvia M.;Alvarez, Jaime L.;Torres, Valerie;Martinez, Ileanne;Santiago, Kiara M.;Ortiz-Marciales, Margarita [Journal of Organic Chemistry,2013,vol. 78,# 11,p. 5314 - 5327]

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