Retinyl propionate synthesis
1synthesis methods
- Product Name:Retinyl propionate
- CAS Number:7069-42-3
- Molecular formula:C23H34O2
- Molecular Weight:342.51
Yield:7069-42-3 98%
Reaction Conditions:
with toluene-4-sulfonic acid in cyclohexane at 70; for 2 h;
Steps:
3
Add 900g vitamin A to the reactor,250g propionic acid, 1g p-toluenesulfonic acid,4L cyclohexane, stirring. 70 reflux water separation,Reaction 2h. After the reaction, wash with water to remove light components,1080g of vitamin A propionate solid was obtained,The content is 96% and the yield is 98%.
References:
Wanhua Chemical Group Co., Ltd.;Lv Yingdong;Wang Zhan;Zhang Tao;Li Yuan CN110950791, 2020, A Location in patent:Paragraph 0073; 0078