(S)-2-AMINO-3-PYRAZOL-1-YL-PROPIONIC ACID synthesis
- Product Name:(S)-2-AMINO-3-PYRAZOL-1-YL-PROPIONIC ACID
- CAS Number:2734-48-7
- Molecular formula:C6H9N3O2
- Molecular Weight:155.15
20945-53-3
22 suppliers
inquiry
2734-48-7
47 suppliers
inquiry
Yield:-
Reaction Conditions:
with hydrogen;palladium on activated charcoal in methanol; for 2 h;
Steps:
2
(S)-2-(benzyloxycarbonylamino)-3-(1H-pyrazol-1-yl)propanoic acid (0.20 g, 0.70 mmol) was hydrogenated in the presence of Pd-C (45 mg) in MeOH (5 mL) at atmospheric pressure for 2 h. The product appeared to be insoluble in MeOH, therefore the reaction mixture was diluted with 5 mL H2O and a few drops of 6N Hcl. The homogeneous solution was filtered through diatomaceous earth (CELITE), and the MeOH removed in vacuo. The remaining solution was frozen and lyophyllized to give a yellow foam (188.9 mg).
References:
US2009/233925,2009,A1 Location in patent:Page/Page column 49
