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944030-47-1

(S)-5-PHENYL-2-(PYRROLIDIN-2-YL)-1H-IMIDAZOLE synthesis

9synthesis methods
tert-butyl (2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

1252037-59-4
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(S)-5-PHENYL-2-(PYRROLIDIN-2-YL)-1H-IMIDAZOLE

944030-47-1
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Yield:944030-47-1 82%

Reaction Conditions:

with trifluoroacetic acid in dichloromethane at 20; for 1 h;

References:

Kang, Iou-Jiun;Hsu, Sheng-Ju;Yang, Hui-Yun;Yeh, Teng-Kuang;Lee, Chung-Chi;Lee, Yen-Chun;Tian, Ya-Wen;Song, Jen-Shin;Hsu, Tsu-An;Chao, Yu-Sheng;Yueh, Andrew;Chern, Jyh-Haur [Journal of Medicinal Chemistry,2017,vol. 60,# 1,p. 228 - 247]