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ChemicalBook CAS DataBase List Z-PRO-NH2

Z-PRO-NH2 synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydroxide / H2O / Ambient temperature
2: 1.) triethylamine, isobutyl chloroformate, 2.) ammonia / 1.) chloroform, 0 deg C, 2 h, 2.) chloroform, RT, overnight

References:

Morikawa;Honda;Endoh -i.;Matsumoto;Akamatsu -i.;Mitsui;Koizumi [Journal of Pharmaceutical Sciences,1991,vol. 80,# 9,p. 837 - 842]

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