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4604-20-0

succinic acid Monohydrazide synthesis

2synthesis methods
-

Yield:4604-20-0 87%

Reaction Conditions:

in acetonitrile at 20; for 24 h;

References:

Rose, Nathan R.;Woon, Esther C. Y.;Tumber, Anthony;Walport, Louise J.;Chowdhury, Rasheduzzaman;Li, Xuan Shirley;King, Oliver N. F.;Lejeune, Clarisse;Ng, Stanley S.;Krojer, Tobias;Chan, Mun Chiang;Rydzik, Anna M.;Hopkinson, Richard J.;Che, Ka Hing;Daniel, Michelle;Strain-Damerell, Claire;Gileadi, Carina;Kochan, Grazyna;Leung, Ivanhoe K. H.;Dunford, James;Yeoh, Kar Kheng;Ratcliffe, Peter J.;Burgess-Brown, Nicola;Von Delft, Frank;Muller, Susanne;Marsden, Brian;Brennan, Paul E.;McDonough, Michael A.;Oppermann, Udo;Klose, Robert J.;Schofield, Christopher J.;Kawamura, Akane [Journal of Medicinal Chemistry,2012,vol. 55,# 14,p. 6639 - 6643] Location in patent:supporting information; experimental part