ChemicalBook CAS DataBase List Sulfamonomethoxine

Sulfamonomethoxine synthesis

1synthesis methods

Product Name:Sulfamonomethoxine
CAS Number:1220-83-3
Molecular formula:C11H12N4O3S
Molecular Weight:280.3

Sodium sulfamethoxazole is commonly used in clinical practice, and the preparation method of sodium sulfamethoxazole includes the following steps:
(1) Add sulfamethoxazole and sodium hydroxide into organic solvent, and stir the reaction for 0.5-2

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

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Yield:-

Reaction Conditions:

with iron;ammonium chloride in water for 10 h;Heating;Yield given;

References:

Luk'yanov, A. V.;Onoprienko, V. S.;Borodina, K. S.;Zasosov, V. A.;Van'kovich, E. V.;et al. [Pharmaceutical Chemistry Journal,1980,vol. 14,# 9,p. 640 - 644][Khimiko-Farmatsevticheskii Zhurnal,1980,vol. 14,# 9,p. 87 - 91]

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