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TRANS-4-N-BOC-AMINOMETHYL-CYCLOHEXANECARBONITRILE synthesis

7synthesis methods
749866-15-7 Synthesis
(4-Carbamoylcyclohexylmethyl)-carbamic acid tert-butyl ester and enantiomer

749866-15-7
19 suppliers
$355.25/1g

TRANS-4-N-BOC-AMINOMETHYL-CYCLOHEXANECARBONITRILE

473923-79-4
31 suppliers
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Yield:473923-79-4 92%

Reaction Conditions:

with ethyl phosphodichloridite;1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane at 20; for 2 h;

References:

Kuo, Chun-Wei;Zhu, Jia-Liang;Wu, Jen-Dar;Chu, Cheng-Ming;Yao, Ching-Fa;Shia, Kak-Shan [Chemical Communications,2007,# 3,p. 301 - 303]

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