3'-Nitroacetophenon
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- CAS-Nr.
- 121-89-1
- Bezeichnung:
- 3'-Nitroacetophenon
- Englisch Name:
- 3-Nitroacetophenone
- Synonyma:
- 1-(3-NITROPHENYL)ETHANONE;M-NITROACETOPHENONE;(3-nitrophenyl)methylketone;usafma-1;USAF ma-1;AKOS 233-65;AURORA 14018;3-Nitroacetofenon;AKOS BBS-00003220;3-NITROACETOPHENONE
- CBNumber:
- CB4400448
- Summenformel:
- C8H7NO3
- Molgewicht:
- 165.15
- MOL-Datei:
- 121-89-1.mol
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3'-Nitroacetophenon Eigenschaften
- Schmelzpunkt:
- 76-78 °C(lit.)
- Siedepunkt:
- 202 °C(lit.)
- Dichte
- 1.3450 (rough estimate)
- Dampfdruck
- 0.32Pa at 25℃
- Brechungsindex
- 1.5468 (estimate)
- Flammpunkt:
- 202°C
- storage temp.
- Sealed in dry,Room Temperature
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Crystalline Powder
- Farbe
- Yellow to yellow-green
- Geruch (Odor)
- Odorless
- Wasserlöslichkeit
- <0.01 g/100 mL at 20 ºC
- BRN
- 743002
- Stabilität:
- Stable. Incompatible with strong oxidizing agents, strong bases.
- InChIKey
- ARKIFHPFTHVKDT-UHFFFAOYSA-N
- LogP
- 1.42
- NIST chemische Informationen
- 3-Nitroacetophenone(121-89-1)
- EPA chemische Informationen
- 3-Nitroacetophenone (121-89-1)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
21 |
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| S-Sätze: |
22-24/25 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
AM9625000 |
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| TSCA |
Yes |
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| HS Code |
29147090 |
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| Giftige Stoffe Daten |
121-89-1(Hazardous Substances Data) |
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| Toxizität |
mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),National Technical Information Service. Vol. AD277-689, |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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3'-Nitroacetophenon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R21:Gesundheitsschädlich bei Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to light beige crystalline powder or yellow needle-like crystals. soluble in hot water and ether, slightly soluble in ethanol. can be volatile with water vapor.
Verwenden
3''-Nitroacetophenone is used as a reactant in the synthesis of fluorine based aminothiazoles with antimicrobial activity.
synthetische
3-Nitroacetophenone is synthesized from acetophenone by nitration.
Synthesis of 3-nitroacetophenone
Vorbereitung Methode
Acetophenone is carefully dissolved in concentrated sulfuric acid at 0 ℃, and
mixed acid is added slowly below 0 ℃. The
crude product is precipitated by quenching into
ice, filtered, and washed acid free. Purification,
mainly from the ortho isomer, is achieved by
recrystallization from ethanol with significant
lowering of the overall yield to ca. 55 %.
Allgemeine Beschreibung
3-nitroacetophenone is a light beige powder. It is an anthropogenic compound which is used as a synthetic intermediate in the production of dyes and other organic compounds. (NTP, 1992)
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Brandgefahr
Flash point data for 3-Nitroacetophenone are not available, however 3-Nitroacetophenone is probably combustible.
läuterung methode
Distil the ketone in steam and crystallise it from EtOH. [Beilstein 7 IV 656.]
3'-Nitroacetophenon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3'-Nitroacetophenon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 481)Lieferanten
121-89-1(3'-Nitroacetophenon)Verwandte Suche:
- 3’-nitroacetophenone[qr]
- 3-Nitroacetofenon
- Acetophenone, 3'-nitro-
- acetophenone,3’-nitro-[qr]
- Ethanone, 1-(3-nitrophenyl)-
- Ethanone,1-(3-nitrophenyl)-
- ethanone,1-(3-nitrophenyl)-[qr]
- m-Acetylnitrobenzene
- Methyl 3-nitrophenyl ketone
- methyl3-nitrophenylketone
- methyl3-nitrophenylketone[qr]
- USAF ma-1
- 3'-Nitroacetophenone Vetec(TM) reagent grade, 98%
- m-Nitroacetophenone
1-(3-Nitrophenyl)ethanone
- usafma-1
- META NITRO ACETOPHENONE
- 6-CHLOROMETHYL-3-FORMYLCHROMONE
- M-Nitroacetophenone, 98% 100GR
- 3'-Nitroacetophenone, 98+%
- m-NITROACETOPHENONE pure
- 3-Acetyl-1-nitrobenzene
- m-Nitroacetophenone,98%
- 1-(3-Nitrophenyl)ethan-1-one, 3-Acetylnitrobenzene, 3-Ethanoylnitrobenzene
- Nitrobenzene between ethyl ketone
- 3'-Nitroacetophenone purum, >=98.0% (GC)
- 3'-Nitroacetophenone ReagentPlus(R), 99%
- 3'-NITROACETOPHENONE
- 3-NITROACETOPHENONE
- 1-Acetyl-3-nitrobenzene
- 3’-nitro-acetophenon
- (3-Nitrophenyl) methyl ketone
- 1-(3-nitrophenyl)-ethanon
- AKOS BBS-00003220
- AKOS 233-65
- LABOTEST-BB LT01895210
- AURORA 14018
- 2-[[1-(3-chlorophenyl)-1,2,4-triazol-3-yl]oxy]propanamide
- 3'-Nitroacetophenone>
- 3-Nitroacetophenone ISO 9001：2015 REACH
- M-NITROACETOPHENONE
- (3-nitrophenyl)methylketone
- 1-(3-NITROPHENYL)ETHANONE
- Paracetamol Impurity 29
- 3-Nitroacetophenone (3NAP)
- 3'-nitroacetophenone
- 121-89-1
- KETONE
- Organic Building Blocks
- Ketones
- C7 to C8
- Carbonyl Compounds
- Building Blocks
- Carbonyl Compounds
- Ketones
- Building Blocks
- C7 to C8
- Carbonyl Compounds
- Chemical Synthesis
