Nefazodone Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Crystalline Solid
Verwenden
A selective serotonin 5-HT2 receptor antagonist. An antidepressant
Biologische Funktion
Although nefazodone (Serzone) is structurally related
to trazodone, it is less sedating. It does not block α
1-
adrenoreceptors, and its use is not associated with priapism.
Nefazodone inhibits the neuronal reuptake of
serotonin and blocks 5HT2A receptors. Its short half-life
requires dosing twice a day. Nefazodone is
not associated with weight gain or sexual dysfunction. It
inhibits the cytochrome P450 3A4 isoenzyme that is responsible
for 50% of known oxidative metabolism, and
therefore, nefazodone can elevate levels of drugs dependent
on this pathway for metabolism.
Nefazodone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
