네파조돈

네파조돈
네파조돈 구조식 이미지
카스 번호:
83366-66-9
한글명:
네파조돈
동의어(한글):
네파조돈
상품명:
Nefazodone
동의어(영문):
SERZONE;Dutonin;Nefadar;BMY-13754;NEFAZODONE;MJ-13754-1;MJ-13754-I;Nefazodone base;l)-5-ethyl-4-(2-phenoxyethyl)-;Nefazodone (base and/or unspecified salts)
CBNumber:
CB5144862
분자식:
C25H32ClN5O2
포뮬러 무게:
470.01
MOL 파일:
83366-66-9.mol

네파조돈 속성

녹는점
180-182°C
끓는 점
599.6±60.0 °C(Predicted)
밀도
1.23±0.1 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMSO: ~11mg/mL( 60 °C)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
pKa 6.5 (Uncertain)
색상
하얀색
CAS 데이터베이스
83366-66-9(CAS DataBase Reference)
NIST
Nefazodone(83366-66-9)

안전

안전지침서 22-24/25
WGK 독일 3
유해 물질 데이터 83366-66-9(Hazardous Substances Data)

네파조돈 C화학적 특성, 용도, 생산

화학적 성질

Crystalline Solid

용도

A selective serotonin 5-HT2 receptor antagonist. An antidepressant

Biological Functions

Although nefazodone (Serzone) is structurally related to trazodone, it is less sedating. It does not block α1- adrenoreceptors, and its use is not associated with priapism. Nefazodone inhibits the neuronal reuptake of serotonin and blocks 5HT2A receptors. Its short half-life requires dosing twice a day. Nefazodone is not associated with weight gain or sexual dysfunction. It inhibits the cytochrome P450 3A4 isoenzyme that is responsible for 50% of known oxidative metabolism, and therefore, nefazodone can elevate levels of drugs dependent on this pathway for metabolism.

네파조돈 준비 용품 및 원자재

원자재

준비 용품


네파조돈 공급 업체

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