p-Hydroxyphenylessigsure
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- CAS-Nr.
- 156-38-7
- Bezeichnung:
- p-Hydroxyphenylessigsure
- Englisch Name:
- 4-Hydroxyphenylacetic acid
- Synonyma:
- P-HYDROXYPHENYLACETIC ACID;PHPA;2-(4-hydroxyphenyl)acetic acid;4-Hydroxybenzeneacetic acid;4-carboxymethylphenol;4-Hydroxyphenylacetic;4-hydrophenylacetic acid;4-hydroxybenzeneaceticacid;Benzeneacetic acid, 4-hydroxy-;NSC 27460
- CBNumber:
- CB6314323
- Summenformel:
- C8H8O3
- Molgewicht:
- 152.15
- MOL-Datei:
- 156-38-7.mol
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p-Hydroxyphenylessigsure Eigenschaften
- Schmelzpunkt:
- 148-151 °C(lit.)
- Siedepunkt:
- 234.6°C (rough estimate)
- Dichte
- 1.2143 (rough estimate)
- Dampfdruck
- 0.007Pa at 25℃
- Brechungsindex
- 1.4945 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- 50g/l
- Aggregatzustand
- Crystalline Powder
- pka
- 4.50±0.10(Predicted)
- Farbe
- White to cream or light tan
- PH
- 2.0-2.4 (30g/l, H2O, 20℃)
- Wasserlöslichkeit
- Soluble in dimethyl sulfoxide and methanol. Slightly soluble in water.
- BRN
- 1448766
- InChIKey
- XQXPVVBIMDBYFF-UHFFFAOYSA-N
- LogP
- 0.75 at 25℃
- CAS Datenbank
- 156-38-7(CAS DataBase Reference)
- NIST chemische Informationen
- Benzeneacetic acid, 4-hydroxy-(156-38-7)
- EPA chemische Informationen
- Benzeneacetic acid, 4-hydroxy- (156-38-7)
p-Hydroxyphenylessigsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
4-Hydroxyphenylacetic acid is a white to cream or light tan crystalline powder. sublimation. Insoluble in cold water, soluble in hot water, ether, ethanol, ethyl acetate. In the case of ferric chloride, it is a purple-green precipitate. It is used as a pharmaceutical raw material for the synthesis of cephalosporin antibiotics, antipyretic analgesics.
Verwenden
A compound present in olive oil. An important fine chemical intermediate with broad prospects for application development.
synthetische
4-Hydroxyphenylacetic acid is synthesized by diazotization and hydrolysis of 4-aminophenylacetic acid.
4-aminophenylacetic acid and alkali solution are prepared into sodium salt, and then sulfuric acid is added. Cool to 0°C, control the temperature at 0-5°C, and add sodium nitrate solution dropwise, and the reaction is completed for 0.5h. The obtained diazonium was added dropwise to dilute sulfuric acid at 90-95°C for about 1 hour, and the reaction was continued for 1 hour. The reaction solution was decolorized and filtered, cooled and extracted with ethyl acetate, and the extract was recovered with ethyl acetate to obtain 4-Hydroxyphenylacetic acid. The yield is about 85%.
Definition
ChEBI: 4-hydroxyphenylacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. It has a role as a plant metabolite, a fungal metabolite, a human metabolite and a mouse metabolite. It is a monocarboxylic acid and a member of phenols. It derives from an acetic acid. It is a conjugate acid of a 4-hydroxyphenylacetate.
läuterung methode
Crystallise the acid from water or Et2O/pet ether. The p-bromophenacyl ester has m 117o (from EtOH). [Beilstein 10 II 112, 10 III 430, 10 IV 543.]
p-Hydroxyphenylessigsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
p-Hydroxyphenylessigsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 715)Lieferanten
156-38-7(p-Hydroxyphenylessigsure)Verwandte Suche:
- (p-hydroxyphenyl)-aceticaci
- 4-Hydroxyphenylacetic acid Vetec(TM) reagent grade, 98%
- Arbidol Impurity F HCl
- Levothyroxine Sodium Impurity d
- NSC 27460
- Acetic acid, (p-hydroxyphenyl)-
- ethanoicacid,4-hydroxyphenyl-
- Parahydroxy phenylacetic acid
- RARECHEM AL BO 0188
- P-HYDROPHENYLACETIC ACID
- AKOS 236-100
- 4-HYDROXYPHENYLACETIC ACID
- 4-HYDROXYPHENYLACETIC ACID, FOR FLUORESC ENCE
- 4-HydroxyphenylacetidAcid
- 4-Hydroxyphenylacetic acid,98%
- HYDROXYPHENYLACETIC ACID, 4-(RG)
- 4-Hydroxyphenylacetic acid, 98% 100GR
- Atenolol iMpurity F(4-Hydroxyphenylacetic acid)
- 4-hydroxy-benzeneaceticaci
- 4-hydroxyphenylethanoicacid
- Hydroxyphenylacetic aci
- 4-Hdroxyphenylacetic acid
- The hydroxy benzene acetic acid
- 4-Hydroxyphenylacetic acid 98%
- p-Hydroxybenzeneacetic acid
- Atenolol Impurity (4-Hydroxyphenylacetic
- Atenolol Impurity K
- 4-HydroxyphenylaceticAcid>
- parahydroxy phenylacetate
- 4-Hydroxyphenylacetin acid
- Name 4-Hydroxyphenylacetic acid
- Atenolol Impurity 12
- p-Hydroxyphenylessigsure
- Qulaity Guaranteed Intermediate Powder 4-Hydroxyphenylacetic Acid CAS 156-38-7 C8h8o3 with Fast Delivery
- 4-Hydroxyphenylacetic Acid D4
- 4-Hydroxyphenylacetic acid, 97%+
- 4-carboxymethylphenol
- 4-Hydroxybenzeneacetic acid
- P-HYDROXYPHENYLACETIC ACID
- PHPA
- 4-hydroxybenzeneaceticacid
- Benzeneacetic acid, 4-hydroxy-
- 2-(4-hydroxyphenyl)acetic acid
- 4-Hydroxyphenylacetic
- 4-hydrophenylacetic acid
- 156-38-7
- HOC6H4CH2CO2H
- Other Fluorescent Labels
- Fluorescent Probes, Labels, Particles and Stains
- Fluorescent Labels
- Biochemicals and Reagents
- BioChemical
- CARBOXYLIC ACID
- C8Fluorescent Probes, Labels, Particles and Stains
- Other Fluorescent Labels
- Carbonyl Compounds
- Carboxylic Acids
- Fluorescent Labels
