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4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on

83-07-8

CAS-Nr.: 83-07-8

Bezeichnung:: 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on

Englisch Name:: 4-Aminoantipyrine

Synonyma:: 4-AAP;AMPYRONE;AMINOANTIPYRINE;4-AMINOPHENAZONE;4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;4-AMINOANTIPYRIN;4-AMINO-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE;4-AMINO-1,5-DIMETHYL-2-PHENYL-1,2-DIHYDRO-PYRAZOL-3-ONE;NSC 60242;Minoazophene

CBNumber:: CB7485059

Summenformel:: C11H13N3O

Molgewicht:: 203.24

MOL-Datei:: 83-07-8.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 400

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on Eigenschaften

Schmelzpunkt:: 105-110 °C(lit.)

Siedepunkt:: 340 C

Dichte: 0.8

Brechungsindex: 1.4930 (estimate)

storage temp.: Keep in dark place,Inert atmosphere,Room temperature

Löslichkeit: H₂O: 0.1 g/mL, clear

pka: pK1: 4.94(+1) (25°C)

Aggregatzustand: Powder or Crystals

Farbe: Yellow to yellow-brown

PH: 7.1 (100g/l, H2O, 20℃)(slurry)

Geruch (Odor): Odorless

Wasserlöslichkeit: ca. 500 g/L (20 ºC)

Merck: 14,591

BRN: 181635

Stabilität:: Stable. May be light sensitive.

LogP: -0.257 (est)

CAS Datenbank: 83-07-8(CAS DataBase Reference)

NIST chemische Informationen: Aminoantipyrene(83-07-8)

EPA chemische Informationen: 4-Aminoantipyrene (83-07-8)

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-36/37/38-20/21/22
S-Sätze:	26-36-36/37/39
WGK Germany	3
RTECS-Nr.	CD2480000
F	8-9-23
Hazard Note	Harmful
TSCA	Yes
HS Code	29331190
Toxizität	LD50 orally in Rabbit: 1700 mg/kg

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H302	Gesundheitsschädlich bei Verschlucken.	Akute Toxizität oral	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P270, P301+P312, P330, P501

Sicherheit

P264	Nach Gebrauch gründlich waschen.
P264	Nach Gebrauch gründlich waschen.
P270	Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312	BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P501	Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

Amber crystalline powder

Application

4-aminoantipyrine is the most widely used analytical reagent for the estimation of phenol. It is used as a reagent for glucose determination in the presence of peroxidase and phenol. It is also used as indicator for trace phenol determinations in water.
Phenolic compounds were determined by buffering the sample to a pH of 10.0 and adding 4-aminoantipyrine to produce a yellow or amber colored complex in the presence of ferricyanide ion. The colour is intensified through extraction of the complex into chloroform. Measurement of this colour quantitatively determines the phenol concentration of the sample.

Verwenden

4-Aminoantipyrine is a metabolite of aminopyrine, having both analgesic and anti-inflammatory properties. It readily forms metal complexes due to its amino nitrogen, a strong coordination site.
4-aminoantipyrine forms Schiff bases when treated with aldehydes/ketones, which are used in chemosensing applications.
Coupling Reagent for Trinder's reagent in colorimetric hydrogen peroxide detectionassays.
Forms highly stable dyes by coupling with Trinder's reagent in presence of Peroxidase and H2O2. Therefore suitable for use in test strip and solution diagnostics.

synthetische

synthesis of 4-aminoantipyrine: Antipyrine is nitrosated by sodium nitrite, reduced by ammonium bisulfite and ammonium sulfite, hydrolyzed by sulfuric acid, and finally neutralized with liquid ammonia to obtain 4-aminoantipyrine.

Definition

ChEBI: 4-aminoantipyrine is a pyrazolone, a member of the class of pyrazoles that is antipyrine substituted at C-4 by an amino group. It is a metabolite of aminopyrine and of metamizole. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antirheumatic drug, a peripheral nervous system drug, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antipyretic, a drug metabolite and a marine xenobiotic metabolite. It is a primary amino compound and a pyrazolone. It derives from an antipyrine.

Allgemeine Beschreibung

4-Aminoantipyrine forms heterocyclic Schiff bases, by reaction with various aldehydes and oximes. These Schiff bases form stable complexes with transition metals.

läuterung methode

It crystallises from EtOH or EtOH/ether. [Beilstein 25 III/IV 3554.]

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Ammoniumhydrogensulfit Iodine solution Natriumnitrit Antipyrine Starch paper Schwefelsure 2,3-Dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-on

Downstream Produkte

4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-on N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamid 1,2-Dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-on AMMONIUM ALGINATE 4-Isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-methoxybenzamide 2-CYANO-N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-ACETAMIDE 3-CHLORO-N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)PROPANAMIDE N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2-(dimethylamino)propionamid

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 400)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	951	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15932	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9347	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58

83-07-8(4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on)Verwandte Suche:

Natrium-(6R-trans)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-(1H-tetrazol-1-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylat Cefazolin Chlordimethylphenylsilan Dimethyl ether Dimethylfumarat Dimethylcarbonat N,N-Dimethyl-phenylendiamin (p) Dimethyl sebacate Dimethylsulfoxid Antipyrine 3,4'-DIAMINODIPHENYLMETHANE Glucosamin Propyphenazon 4,4'-Diaminodiphenylsulfon N,N-Dimethylformamid Paracetamol 4,4'-Methylenbis[1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-on] Aminotransferase, Alanin-

4-Amine-2,3-dimethyl-lphenyl-5-pyrazolone-[5],Ampyrone
4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-on
AKOS BBS-00007964
AMINOANTIPYRINE, 4-
AMINOANTIPYRINE REAGENT
AMINOPHENYZONE
1-PHENYL-2,3-DIMETHYL-4-AMINOPYRAZOLONE
1,5-DIMETHYL-2-PHENYL-4-AMINOPYRAZOLONE
4-AMINOANTIPYRENE
4-AMINOANTIPYRINE
4-AMINOANTIPYRINE REAGENT
4-AMINO-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLINE-5-ONE
4-AMINO-1,3-DIMETHYL-2-PHENYL-3-PYRAZOLONE
4-AMINO-1,5-DIMETHYL-2-PHENYL-3H-PYRAZOL-3-ONE
4-Amino-1,5-dimethyl-2-phenyl-3-pyrazolone
1,5-dimethyl-2-phenyl-4-aminopyrazolin
4-AMINOANTIPYRINE [4-AMINO-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE]
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone
1,2-Dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one
1-Phenyl-2,3-dimethyl-4-amino-5-pyrazolone
4-Amino-2,3-dimethyl-1-phenyl-5-pyrazolone
4-Aminoantipyrine [for Biochemical Research]
4-Aminoantipyrine,98%
4-Aminoantipyrine;4-aminophenazone
4-AMINO-2,3-DIMETHYL-1-PHENYL-3-PYR-AZOL IN-5-ON R. G., REAG. PH. EUR. I
4-AMINOANTIPYRINE FREE BASE
4-AminoantipyrinePuriss
4-AminoantipyrinePuriss(4-Aminophenazone)
4-AMINOBENZENE SULFONIC ACID( Sulphanilic Acid)
4-Amino-1,5-dimethyl-2-phenyl-4-pyrazolin-3-one
Aminoantipyrene
4-amino antipyirine
4-AMINOANTIPYRIDINE (AMPYRONE)
AMINOANTIPYRINE, 4-(RG)
4-Aminoantipyrine,4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone
4-Aminoantipyrine p.a.
AMINOANTIPYRINE, 4-(AMPYRONE)(RG)
4-AMINOANTIPYRINERESEARCH GRADE
1,5-Dimethyl-2-phenyl-4-aminopyrazoline
1-Phenyl-2,3-dimethyl-4-aminopyrazloone-[5]
3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-
3-Pyrazolin-5-one, 4-amino-2,3-dimethyl-1-phenyl-
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 4-Aminophenazone
(2,3-Dihydro-1,5-diMethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)aMine
Minoazophene
NSC 60242
(2,3-Dihydro-1,5-(diMethyl-d3)-3-oxo-2-phenyl-1H-pyrazol- 4-yl)aMine
1,2-Dihydro-1,5-(diMethyl-d3)-2-phenyl-4-aMino-3H-pyrazol-3-one
4-AMino-1,2-dihydro-1,5-(diMethyl-d3)-2-phenyl-3H-pyrazol-3-one
4-AMinoantipyrine-d3
4-Aminophenazone 4-AA
4-AMinoantipyrine
4-AMinoantipyrine, 98% 100GR
4-AMinoantipyrine, 98% 25GR
4-AMINO-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLI
4-Aminoantipyrine puriss. p.a., Reag. Ph. Eur., >=99%
FORMAMIDE DEIONIZED ULTRA PURE GRADE
4-Aminoantipyine