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Dexamethason-21-acetat

Dexamethasone-17-acetate Struktur
1177-87-3
CAS-Nr.
1177-87-3
Bezeichnung:
Dexamethason-21-acetat
Englisch Name:
Dexamethasone-17-acetate
Synonyma:
DEXAMETHASONE ACETATE;DEXAMETHASON ACETATE;DEXAMETHASONE 21-ACETATE;9-fluoro-11β,17-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate;Dectan;Panasone;Dectancyl;NSC 39471;Decadronal;Decadron-la
CBNumber:
CB9703269
Summenformel:
C24H31FO6
Molgewicht:
434.5
MOL-Datei:
1177-87-3.mol
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Dexamethason-21-acetat Eigenschaften

Schmelzpunkt:
238-240 °C(lit.)
Siedepunkt:
579.4±50.0 °C(Predicted)
alpha 
D25 +73° (chloroform) (Arth, 1958); D +77.6° (Oliveto)
Dichte
1.1517 (estimate)
Brechungsindex
87 ° (C=1, Dioxane)
storage temp. 
2-8°C
Löslichkeit
Soluble at 100 mg/ml in acetone
Aggregatzustand
Powder
pka
12.08±0.70(Predicted)
Farbe
White
Wasserlöslichkeit
13mg/L(25 ºC)
Merck 
2943
BRN 
2342608
CAS Datenbank
1177-87-3(CAS DataBase Reference)
NIST chemische Informationen
Prednisolone, 9alpha-fluoro-16alpha-methyl-, acetate(1177-87-3)
EPA chemische Informationen
Dexamethasone-21-acetate (1177-87-3)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 43
S-Sätze: 36/37
WGK Germany  3
RTECS-Nr. TU4050000
TSCA  Yes
HS Code  29372290

Dexamethason-21-acetat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R43:Sensibilisierung durch Hautkontakt möglich.

S-Sätze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Chemische Eigenschaften

Off-White Solid

Verwenden

Protected Dexamethasone, a glucocorticoid anti-inflammatory agent.

Sicherheitsprofil

Experimental teratogenic and reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F-.

läuterung methode

Dexamethasone 21-acetate is purified on neutral Al2O3 using CHCl3 as eluent, the fractions are evaporated, and the residue is recrystallised from CHCl3. It has max at 239nm. [Oliveto et al. J Am Chem Soc 8 0 4431 1958]. [Beilstein 8 IV 3501.]

Dexamethason-21-acetat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Progesteron Ethandiol Fluorwasserstoff Brommethan 11β,16α,17,21-Tetrahydroxypregna-1,4-dien-3,20-dion

Downstream Produkte

9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione21-phosphate piperazine salt Dexamethason

Dexamethason-21-acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 522)Lieferanten
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1177-87-3(Dexamethason-21-acetat)Verwandte Suche:

Dexamethason-21-(3-phenylpropionat) Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-[(3-sulfobenzoyl)oxy]-, Mononatriumsalz, (11β,16α)- 9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-dien-3,20-dion 17,21-Dihydroxy-16α-methylpregna-1,4,9(11)-trien-3,20-dion 9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Desoximetason 9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17-valerat 17-α,21-Dihydroxy-16-α-methylpregna-1,4,9(11)-trien-3,20-dion-21-acetat 9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Dexamethason-21-pivalat Betamethason 9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat) 9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(3,3-dimethylbutyrat) Dexamethason-21-acetat 6α,9-Difluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-acetat Dexamethason Methylprednisolon-21-acetat Methylprednisolon
  • 20-dione,9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-pregna-4-diene-3
  • 9alpha-Fluoro-16alpha-methylprednisolone acetate
  • 9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione21-acetate
  • 9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
  • 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
  • 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-acetate
  • 9-Fluoro-11-beta,17,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione acetate
  • Dalalone D.P.
  • Dalalone L.A.
  • Decadronal
  • Decadron-L.A.
  • Decadron-la
  • Dectan
  • Dectancyl
  • Dexacortisyl
  • Dex-Cortidelt acetate
  • Fortecortin
  • Fortecortin (crystal suspension)
  • 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate
  • Dexamethasone Acetate, Anhydrous, Micronized
  • 21-Acetoxy-9α-fluoro-11β,17α-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
  • 9-Fluoro-3,20-dioxo-16α-methylpregna-1,4-diene-11β,17,21-triol 21-acetate
  • Dexametasone acetate
  • MPB Dexamethasone-21-acetate
  • 21-O-Acetyl Dexamethasone
  • 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
  • Dexamethasone 21-acetate,9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
  • Dexamethasone Acetate (200 mg)
  • Dexamethasone Acetate (200 mg)H0E3390.996mg/mg(dr)
  • Dexamethasone-17-ace
  • 9-ALPHA -FLUORO-11BETA 17ALPHA 21-TRIHYDROXY-16ALPHA -METHYL-1 4-PREGNADIENE-3 20-DIONE
  • 2-((8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
  • Dexamethasone 21-Acetate Solution, 100ppm
  • Dexamethasone Acetate Dexamethasoneacetate dexamethasone-21-acetate
  • dexamethasone-17-acetate
  • 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-ACETATE
  • PREDNISOLONE F ACETATE
  • 9ALPHA-FLUORO-16ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE-21-ACETATE
  • 9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA,17-ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE ACETATE
  • 9ALPHA-FLUORO-16ALPHA-METHYLPREDNISOLONE-21-ACETATE
  • 9 ALPHA-FLUORO-11 BETA,17 ALPHA,21-TRIHYDRO-16 ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE-21-ACETATE
  • 9a-fluoro-16a-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate
  • Panasone
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11beta,16alpha)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-, 21-acetate
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-, acetate
  • DEXAMETHASON 21-ACETATE VETRANAL, 250 MG
  • DEXAMETHASONE ACETATE EPD(CRM STANDARD)
  • DEXAMETHASONE ACETATE USP(CRM STANDARD)
  • DEXAMETHASONE ACETATE WHO(CRM STANDARD)
  • DEXAMETHASONE 21-ACETATE, USP
  • 9α-fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate
  • DEXAMETHASONEACETATE,ANHYDROUS,MICRONIZED,USP
  • 16α-Methyl-9α-fluoroprednisolone 21-acetate
  • NSC 39471
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 21-acetate (6CI, 8CI)
  • 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methyl-1,4-pregnadiene-3,20-dione 21-Acetate
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