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Ibudilast

CAS No.50847-11-5
Chemical Name:Ibudilast
Synonyms:Ketas;KC-404;AV 411;Pinatos;Eyevinal;IBUDILAST;lbudilast;IBUDILAST-D7;Ibudilast (KC-404);2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine
CBNumber:CB0145945
Molecular Formula:C14H18N2O
Formula Weight:230.31
MOL File:50847-11-5.mol
Ibudilast Property
mp : 53-54°C
density : 1.09
storage temp. : 2-8°C
solubility : DMSO: 28 mg/mL, soluble
form : solid
color : white
CAS DataBase Reference: 50847-11-5(CAS DataBase Reference)
Safety
Hazard Codes : Xn
Risk Statements : 22-36/37/38
Safety Statements : 26-36
WGK Germany : 3
RTECS : UR0711200

Ibudilast Chemical Properties,Usage,Production

Chemical Properties
White Solid
Usage
a phosphodiesterase inhibitor with anti-inflammatory activity
Usage
A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral)
Biological Activity
Phosphodiesterase inhibitor (IC 50 values are 53, 35, 48, 12 and 10 mM for PDE Ia, II, III, IV and V respectively). Inhibits platelet aggregation and is an orally-active cerebral vasodilator, bronchodilator and antiallergic agent.
Ibudilast Preparation Products And Raw materials
Raw materials
Sodium acetate 2-Picoline Isobutyric anhydride
Preparation Products
Ibudilast Suppliers      Global( 95)Suppliers     
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GIHI CHEMICALS CO.,LTD 0086-571-862173900086-571-86217391Sales@gihichem.comCHINA 890 58
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J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833+86-10-82849933jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96869 76
Changzhou Sunchem Pharmaceutical Chemical Material Co., Ltd 85195575; 85195565;85195528+86-519-85195585info@sunkechem.comCHINA 106 69
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-62670790(Beijing)sh@meryer.com; sz@meryer.comCHINA 40414 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、803、804、807 Mobile:1893055203786-21-503281093bsc@sina.comCHINA 15993 69
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BeiJing Hwrk Chemicals Limted 4006990298 010-57411839 020-31335234 021-51691807010-87653215 0757-86311057 021-55236763sales@hwrkchemical.comCHINA 13348 55
Energy Chemical 021-58432009 / 400-005-6266021-58436166-800info@energy-chemical.comCHINA 44202 61
 
50847-11-5(Ibudilast)Related Search:
Ibudilast Bensulfuron methyl Citric acid monohydrate Parathion-methyl Kresoxim-methyl Thiophanate-methyl ULINASTATIN Cefazolin 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Methylparaben Cilastatin Imipenem-Cilastatin sodium hydrate Methyl Methyl bromide Methyl acrylate Isobutyryl chloride Naphazoline hydrochloride METHYL THIOPHENE-2-CARBOXYLATE
Phosphodiesterase Inhibitors Cyclic Nucleotide Metabolism G Proteins and Cyclic Nucleotides IBUDILAST IBUDILAST-D7 KC-404 1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL] 2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL]-1-PROPANONE BioChemical Cell Signaling and Neuroscience Cell Biology 3-ISOBUTYRYL-2-ISOPROPYLPYRAZOLO(1,5-A)PYRIDINE 50847-11-5 2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-1-propanon 5-a)pyridine,3-isobutyryl-2-isopropyl-pyrazolo( lbudilast 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone, 3-isobutyrl-2-isopropylpyrazolo[1,5-a]pyridine, KC-404, Ketas 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-α]pyridin-3-yl]-1-propanone, 3-isobutyrl-2-isopropylpyrazolo[1,5-α]pyridine, KC-404, Ketas Intermediates & Fine Chemicals Pharmaceuticals 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, KC-404, 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone Cyclic Nucleotide related 3-Isobutyryl-2-isopropy-lpyrazolo[1,5-α]pyridine Ketas Eyevinal 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methyl-1-propanone Pinatos Ibudilast,2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, KC-404 Amines Heterocycles 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-Methylpropan-1-one AV 411 Ibudilast (KC-404)
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