ChemicalBook >> CAS DataBase List >>Methyl 3-amino-4-methylthiophene-2-carboxylate

Methyl 3-amino-4-methylthiophene-2-carboxylate

Methyl 3-amino-4-methylthiophene-2-carboxylate structure

CAS No.: 85006-31-1

Chemical Name:: Methyl 3-amino-4-methylthiophene-2-carboxylate

Synonyms: 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER;3-Amino Articaine;3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER;M3A4MT2C;Articaine-002;Articaine Impurity I;Articaine Impurity 9;LABOTEST-BB LT00453517;Articaine EP Impurity I;Articaine intermediate E

CBNumber:: CB0189112

Molecular Formula:: C7H9NO2S

Molecular Weight:: 171.22

MDL Number:: MFCD00051822

MOL File:: 85006-31-1.mol

MSDS File:: SDS

Last updated:2023-10-17 13:38:40

Request For Quotation

Methyl 3-amino-4-methylthiophene-2-carboxylate Properties

Melting point	85-88 °C (lit.)
Boiling point	318.6±37.0 °C(Predicted)
Density	1.264±0.06 g/cm3(Predicted)
Flash point	>100°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	1.71±0.10(Predicted)
form	Solid
color	Pale Yellow
Water Solubility	1g/L at 35℃
BRN	973196
InChIKey	YICRPERKKBDRSP-UHFFFAOYSA-N
LogP	1.28
CAS DataBase Reference	85006-31-1(CAS DataBase Reference)
FDA UNII	3LA24473AS
NIST Chemistry Reference	Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25-22

WGK Germany

Hazard Note

Irritant

HS Code

29349990

NFPA 704

	1
2		0

Methyl 3-amino-4-methylthiophene-2-carboxylate price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	546658	Methyl 3-amino-4-methylthiophene-2-carboxylate 97%	85006-31-1	5g	$33.2	2024-03-01	Buy
Sigma-Aldrich	546658	Methyl 3-amino-4-methylthiophene-2-carboxylate 97%	85006-31-1	25g	$127	2024-03-01	Buy
TCI Chemical	M1772	Methyl 3-Amino-4-methylthiophene-2-carboxylate >98.0%(GC)	85006-31-1	5g	$29	2024-03-01	Buy
TCI Chemical	M1772	Methyl 3-Amino-4-methylthiophene-2-carboxylate >98.0%(GC)	85006-31-1	25g	$101	2024-03-01	Buy
Alfa Aesar	A10115	Methyl 3-amino-4-methylthiophene-2-carboxylate, 98%	85006-31-1	5g	$59.2	2021-12-16	Buy

Product number	Packaging	Price	Buy
546658	5g	$33.2	Buy
546658	25g	$127	Buy
M1772	5g	$29	Buy
M1772	25g	$101	Buy
A10115	5g	$59.2	Buy

Methyl 3-amino-4-methylthiophene-2-carboxylate Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

Methyl 3-Amino-4-methylthiophene-2-carboxylate is a versatile reactant used in various syntheses. It is used in the preparation of (oxalylamino)benzoic acids and (carboxyheteroarylamino)oxalic acids as selective and orally bioavailable nonpeptide inhibitors of protein-tyrosine phosphatase 1B.

Application

methyl 3-amino-4-methylthiophene-2-carboxylate is the starting material used in the synthesis of the local anesthetic articaine.
7-Methylthieno[3,2-d]pyrimidin-4(3H)-one was prepared using methyl 3-amino-4-methylthiophene-2-carboxylate.
The reaction of 4-bromotoluene (0.171 g, 1 mmol), methyl 3-amino-4-methylthiophene-2-carboxylate(0.342 g, 2 mmol) and KOAc (0.196 g, 2 mmol) in the presence of PdCl(C3H5)(dppb) (12.2 mg, 0.02mmol) in DMAc at 120 °C affords the corresponding Methyl 3-amino-4-methyl-5-p-tolylthiophene-2-carboxylate in 81% (0.212 g) isolated yield.

Definition

ChEBI: Methyl 3-amino-4-methylthiophene-2-carboxylate is a thiophenecarboxylic acid.

Methyl 3-amino-4-methylthiophene-2-carboxylate synthesis

Synthesis of Methyl 3-amino-4-methylthiophene-2-carboxylate from Methyl 2-Methyl-3-Oxo-Tetrahydrothiophene-2-Carbonate

Methyl 3-amino-4-methylthiophene-2-carboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Sodium hydride Ethanol Hydroxylamine hydrochloride Methyl methacrylate

Methyl 2-Methyl-3-Oxo-Tetrahydrothiophene-2-Carbonate 4-METHYL-3-AMINO-2-(METHOXYCARBONYL)-4,5-DIHYDROTHIOPHENE

1of2

Preparation Products

Thieno[3,2-d]pyrimidine-7-carboxylic acid, 4-chloro- METHYL 3-CHLORO-4-METHYLTHIOPHENE-2-CARBOXYLATE Methyl 3-dimethylamino-4-methylthiophene-2-carboxylate, 97% Thieno[3,2-d]pyriMidine, 2-chloro-7-Methyl-4-(4-Morpholinyl)- 7-(BROMOMETHYL)-2-CHLOROTHIENO[3,2-D]PYRIMIDINE

7-Methylthieno[3,2-d]pyrimidine-2,4-diol tert-butyl 4-methylthiophen-3-ylcarbamate 5-Chlorothieno[3,2-b]pyridine-3-carboxylic acid

1of2

Methyl 3-amino-4-methylthiophene-2-carboxylate Suppliers

Global( 394)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1100	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	811	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Hebei Xinsheng New Material Technology Co., LTD.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58

View Lastest Price from Methyl 3-amino-4-methylthiophene-2-carboxylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-10-17	Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1	US $35.00-25.00 / kg	1kg	99%	20 Ton	Hebei Xinsheng New Material Technology Co., LTD.
2023-09-15	Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1	US $0.00-0.00 / kg	1kg	99.9%	20 tons	Hebei Xinsheng New Material Technology Co., LTD.
2023-08-30	Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
US $35.00-25.00 / kg
99%
Hebei Xinsheng New Material Technology Co., LTD.

Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
US $0.00-0.00 / kg
99.9%
Hebei Xinsheng New Material Technology Co., LTD.

Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Methyl 3-amino-4-methylthiophene-2-carboxylate Spectrum

Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1)IR

85006-31-1(Methyl 3-amino-4-methylthiophene-2-carboxylate)Related Search:

Methyl 4-(bromomethyl)benzoate Methyl anthranilate METSULFURON METHYL Basic Violet 1 Methyl salicylate

Methanol Kresoxim-methyl Glycine Methylparaben Methyl 4-methylbenzoate

3-AMINOTHIOPHENE 2-Methylthiophene Methyl acrylate RESMETHRIN Tribenuron methyl

Methyl carbamate Methyl METHYL 3-AMINO-4-CYANOTHIOPHENE-2-CARBOXYLATE

1of4

M3A4MT2C METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLATE Methyl 3-amino-4-methyl-2-thenoate METHYL 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLATE LABOTEST-BB LT00453517 3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Methyl 3-Amino-4-Methylthiophen-2-Carboxylate METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBO 3-Amino-4-Methyl-2-ThiophenecarboxylicMethylester Articaine intermediate E 3-Amino-2-methoxycarbonyl-4-methylthiophene 3-Amino-2-carbomethoxy-4-methylthiophen 3-Amino-4-methylthiophene-2-carboxylic 2-Thiophenecarboxylic acid, 3-amino-4-methyl-, methyl ester 4-Methyl-3-aminothiophene-2-carboxylic acid methyl ester Methyl 3-amino-4-methylthiophene-2-carboxylate ,99% 3-AMino-4-Methyl-2-thiophene carboxylic acid ester 3-Amino-2-(methoxycarbonyl)-4-methylthiophene, Methyl 3-amino-4-methyl-2-thenoate Articaine IMpurity I (Methyl 3-AMino-4-Methylthiophene-2-Carboxylate) Methyl 3-AMino-4-Methylthiophene-2-carboxylate , 98.0%(GC) Methyl3-amino-4-methylthiophene-2-carboxylate,98% Methyl 3-amino-4-methylthiophene-2-carboxylate(Articaine Intermediates) 3-AMINO 4-METHYL-2-THIOPHENE CARBOXYLICACID METHYL ESTER IMPORTED VIDE B/E 3189721/ 06.11.2015][CLEAR AGAINST ADVANCE L Articaine Impurity 9(Articaine EP Impurity I） Articaine EP Impurity I Methyl3-Amino-4-methylthiophene-2-carboxylate> Articaine-002 Articaine Impurity I 3- amino-4-methyl thiophene - 2-carboxylate, methyl ester Methyl 3-amino-4-methylthiophene-2-carboxylate ISO 9001：2015 REACH Articaine Impurities1819 Articaine Impurity 9 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER 3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER 3-Amino Articaine Articaine Hydrochloride EP Impurity I 85006-31-1 C7H9SNO2 Heterocyclic Building Blocks Thiophenes Building Blocks Thiophenes & Benzothiophenes Building Blocks C7 to C9 Chemical Synthesis Heterocyclic Building Blocks Thiophenes Thiophen Esters Thiophenes & Benzothiophenes Thiophene&Benzothiophene Organic acids API intermediates 1