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ChemicalBook >> CAS DataBase List >> 2,4,7-Triamino-6-phenylpteridine

2,4,7-Triamino-6-phenylpteridine

CAS No. 396-01-0
Chemical Name: 2,4,7-Triamino-6-phenylpteridine
Synonyms: ditak;diren;dyren;dytac;teriam;ADEMINE;diurene;noridil;noridyl;skf8542
CBNumber: CB0663775
Molecular Formula: C12H11N7
Formula Weight: 253.26
MOL File: 396-01-0.mol
2,4,7-Triamino-6-phenylpteridine Property
Melting point : 316°C
Fp : 11 °C
storage temp. : 2-8°C
solubility : formic acid: soluble200 mg + 4 mL warm Formic Acid, clear, yellow-green
Water Solubility : <0.1 G/100 ML AT 20 ºC
Merck : 14,9599
BRN : 266723
CAS DataBase Reference: 396-01-0(CAS DataBase Reference)
NIST Chemistry Reference: Triamterene(396-01-0)
EPA Substance Registry System: 2,4,7-Pteridinetriamine, 6-phenyl-(396-01-0)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes : Xn,T,F
Risk Statements : 22-36/37/38-36/38-23/25-39/23/24/25-23/24/25-11
Safety Statements : 26-36/37/39-45-33-24-16-7-36/37
RIDADR : 2811
WGK Germany : 3
RTECS : UO3470000
HazardClass : 6.1(b)
PackingGroup : III
Hazardous Substances Data: 396-01-0(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

2,4,7-Triamino-6-phenylpteridine Chemical Properties,Usage,Production

Chemical Properties
Yellow Solid
Uses
Triamterene is a potassium-sparing diuretic ie, it inhibits the urinary excretion of potassium
Uses
Triamterene is a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.
General Description
Odorless yellow powder or crystalline solid. Melting point 316°C. Almost tasteless at first and with a slightly bitter aftertaste. Acidified solutions give a blue fluorescence. Used as a diuretic drug.
Air & Water Reactions
Sensitive to light; slowly oxidized upon exposure to air. Insoluble in water.
Reactivity Profile
2,4,7-Triamino-6-phenylpteridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for 2,4,7-Triamino-6-phenylpteridine are not available; however, 2,4,7-Triamino-6-phenylpteridine is probably combustible.
2,4,7-Triamino-6-phenylpteridine Preparation Products And Raw materials
Raw materials
phenylacetonitrile 2,4,6-Triaminopyrimidine Sodium ethoxide Disodium edetate dihydrate Ethyl cyanoacetate
Preparation Products
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396-01-0 6-PHENYL-PTERIDINE-2,4,7-TRIAMINE 6-PHENYL-2,4,7-PTERIDINETRIAMINE 6-PHENYL-2,4,7-TRIAMINO PTERIDINE ADEMINE Cell Biology Cell Signaling and Neuroscience BioChemical 2,4,7-TRIAMINO-6-PHENYLPTERIDINE TRIAMTERENE Voltage-gated Ion Channels Sodium Channel Modulators Ion Channels Other Sodium Channel Modulators Monovalent Ion Channels 2,4,7-triamino-6-fenilpteridina 2,4,7-triamino-6-phenyl-pteridin 7-pteridinetriamine,6-phenyl-4 diren ditak diurene dyren dyrenium dytac jatropur ncic56042 noridil noridyl pterofen pterophene skf8542 taturil teriam teridin triampur triamteren triamteril triamterilcomplex tri-span triteren AMINE Weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys. TRIAMTERENE SODIUM CHANNEL BLOCKE C12H11N7 TRIAMTERENUM 2,4,7-Pteridinetriamine, 6-phenyl- TRIAMTERENE,USP PTERIDINE,2,4,7-TRIAMINO-6-PHENYL- 6-PHENYL-2,4,7-TRIAMINOPTERIDINE (SEE 1843) Intermediates & Fine Chemicals Pharmaceuticals Ion transporter and other ion channel 2,4,7-Triamino-6-phenylteridine (2,4-diamino-6-phenyl-pteridin-7-yl)amine Triamterene,2,4,7-Triamino-6-phenylpteridine Triamterene (200 mg) Aromatics Bases & Related Reagents
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