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ChemicalBook >> CAS DataBase List >> 2,4,7-Triamino-6-phenylpteridine

2,4,7-Triamino-6-phenylpteridine

CAS No.396-01-0
Chemical Name:2,4,7-Triamino-6-phenylpteridine
Synonyms:ditak;diren;dyren;dytac;teriam;ADEMINE;diurene;noridil;noridyl;skf8542
CBNumber:CB0663775
Molecular Formula:C12H11N7
Formula Weight:253.26
MOL File:396-01-0.mol
2,4,7-Triamino-6-phenylpteridine Property
Melting point : 316°C
Fp : 11 °C
storage temp. : 2-8°C
Water Solubility : <0.1 G/100 ML AT 20 ºC
Merck : 14,9599
BRN : 266723
CAS DataBase Reference: 396-01-0(CAS DataBase Reference)
NIST Chemistry Reference: Triamterene(396-01-0)
EPA Substance Registry System: 2,4,7-Pteridinetriamine, 6-phenyl-(396-01-0)
Safety
Hazard Codes : Xn,T,F
Risk Statements : 22-36/37/38-36/38-23/25-39/23/24/25-23/24/25-11
Safety Statements : 26-36/37/39-45-33-24-16-7-36/37
RIDADR : 2811
WGK Germany : 3
RTECS : UO3470000
HazardClass : 6.1(b)
PackingGroup : III
Hazardous Substances Data: 396-01-0(Hazardous Substances Data)

2,4,7-Triamino-6-phenylpteridine Chemical Properties,Usage,Production

Chemical Properties
Yellow Solid
Usage
Triamterene is a potassium-sparing diuretic ie, it inhibits the urinary excretion of potassium
Usage
Triamterene is a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.
General Description
Odorless yellow powder or crystalline solid. Melting point 316°C. Almost tasteless at first and with a slightly bitter aftertaste. Acidified solutions give a blue fluorescence. Used as a diuretic drug.
Air & Water Reactions
Sensitive to light; slowly oxidized upon exposure to air. Insoluble in water.
Reactivity Profile
2,4,7-Triamino-6-phenylpteridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for 2,4,7-Triamino-6-phenylpteridine are not available; however, 2,4,7-Triamino-6-phenylpteridine is probably combustible.
2,4,7-Triamino-6-phenylpteridine Preparation Products And Raw materials
Raw materials
phenylacetonitrile 2,4,6-Triaminopyrimidine Sodium ethoxide Disodium edetate dihydrate Ethyl cyanoacetate
Preparation Products
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396-01-0 6-PHENYL-PTERIDINE-2,4,7-TRIAMINE 6-PHENYL-2,4,7-PTERIDINETRIAMINE 6-PHENYL-2,4,7-TRIAMINO PTERIDINE ADEMINE Cell Biology Cell Signaling and Neuroscience BioChemical 2,4,7-TRIAMINO-6-PHENYLPTERIDINE TRIAMTERENE Voltage-gated Ion Channels Sodium Channel Modulators Ion Channels Other Sodium Channel Modulators Monovalent Ion Channels 2,4,7-triamino-6-fenilpteridina 2,4,7-triamino-6-phenyl-pteridin 7-pteridinetriamine,6-phenyl-4 diren ditak diurene dyren dyrenium dytac jatropur ncic56042 noridil noridyl pterofen pterophene skf8542 taturil teriam teridin triampur triamteren triamteril triamterilcomplex tri-span triteren AMINE Weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys. TRIAMTERENE SODIUM CHANNEL BLOCKE C12H11N7 TRIAMTERENUM 2,4,7-Pteridinetriamine, 6-phenyl- TRIAMTERENE,USP PTERIDINE,2,4,7-TRIAMINO-6-PHENYL- 6-PHENYL-2,4,7-TRIAMINOPTERIDINE (SEE 1843) Intermediates & Fine Chemicals Pharmaceuticals Ion transporter and other ion channel 2,4,7-Triamino-6-phenylteridine (2,4-diamino-6-phenyl-pteridin-7-yl)amine Triamterene,2,4,7-Triamino-6-phenylpteridine Triamterene (200 mg) Aromatics Bases & Related Reagents
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