Hymexazol
- CAS No.
- 10004-44-1
- Chemical Name:
- Hymexazol
- Synonyms
- HYMEXAZOLE;5-METHYLISOXAZOL-3-OL;3-HYDROXY-5-METHYLISOXAZOLE;TACHIGALOZE;HYDROXYISOXAZOLE;5-Hydroxy-3-methylisoxazole;bucid;f-319;T 319;bucide
- CBNumber:
- CB1754230
- Molecular Formula:
- C4H5NO2
- Molecular Weight:
- 99.09
- MDL Number:
- MFCD00144468
- MOL File:
- 10004-44-1.mol
- MSDS File:
- SDS
| Melting point | 80°C |
|---|---|
| Boiling point | 185.54°C (rough estimate) |
| Density | 1.2992 (rough estimate) |
| vapor pressure | 0.182 Pa (25 °C) |
| refractive index | 1.4170 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in alcohol, acetone, THF, chloroform |
| form | Powder |
| pka | 5.91 (weak acid) |
| Water Solubility | 65,100 mg l-1 (20 °C) |
| color | White to Orange |
| Sensitive | Light Sensitive |
| Merck | 14,4856 |
| InChIKey | KGVPNLBXJKTABS-UHFFFAOYSA-N |
| CAS DataBase Reference | 10004-44-1(CAS DataBase Reference) |
| EWG's Food Scores | 1-2 |
| FDA UNII | 20T2M875LO |
| EPA Substance Registry System | Hymexazol (10004-44-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H317-H318-H361d-H411 | |||||||||
| Precautionary statements | P273-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-41-52/53 | |||||||||
| Safety Statements | 26-39-61 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NY2932000 | |||||||||
| HS Code | 29349990 | |||||||||
| Toxicity | LD50 in male, female mice, rats (mg/kg): 2148, 1968, 4678, 3909 orally; 1297, 1167, 1924, 1884 s.c.; 445, 514, >1000, >1000 i.v.; in rats, rabbits (mg/kg): >10000, >2000 dermally (Nakamura, 1978) | |||||||||
| NFPA 704 |
|
Hymexazol price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H3275 | 3-Hydroxy-5-methylisoxazole ≥90% | 10004-44-1 | 50mg | $131 | 2024-03-01 | Buy |
| Sigma-Aldrich | H3275 | 3-Hydroxy-5-methylisoxazole ≥90% | 10004-44-1 | 250mg | $450 | 2024-03-01 | Buy |
| TCI Chemical | H1348 | 3-Hydroxy-5-methylisoxazole >98.0%(GC) | 10004-44-1 | 5g | $42 | 2024-03-01 | Buy |
| TCI Chemical | H1348 | 3-Hydroxy-5-methylisoxazole >98.0%(GC) | 10004-44-1 | 25g | $137 | 2024-03-01 | Buy |
| Alfa Aesar | 044450 | 3-Hydroxy-5-methylisoxazole, 97% | 10004-44-1 | 5g | $53.1 | 2024-03-01 | Buy |
Hymexazol Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Agricultural fungicide and plant growth regulator.
Uses
Pesticide.
Uses
Hymexazol is used to control soil-borne diseases caused by Fusarium, Aphanomyces, Pythium, Corficium and Typhula spp. in rice, sugar beet, fodder beet, vegetables, cucurbits, ornamentals, carnations and forest tree seedlings. It is also used as a seed dressing and stimulates some plant growth.
Definition
ChEBI: A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals.
Synthesis Reference(s)
The Journal of Organic Chemistry, 48, p. 4307, 1983 DOI: 10.1021/jo00171a030
Metabolic pathway
Degradation of hymexazol in soil gave acetoacetamide and the product of rearrangement, 5-methyl-2(3H)-oxazolone.H owever, in plants the fungicide was principally converted into its O- and N-glucoside conjugates in the roots and shoots. The two main metabolites of hymexazol found in the urine of rats were the O-glucuronide and sulfate conjugates.
Degradation
Hymexazol is stable under alkaline conditions and relatively stable in acidic conditions. It is stable to sunlight and heat (PM). It should be noted that the parent molecule is tautomeric. Hymexazol is highly volatile and will be lost by volatilisation unless it is covered or incorporated into soil. The fungicide was completely biodegraded in natural water at 30 °C in 2 weeks and at 10-13 °C in 2 months (Rebenok and Kolesnikova, 1983). Hymexazol is stable in sunlight but it is readily degraded by ultraviolet light. Photolysis of an aqueous solution of the fungicide at 253.7 nm, using a low pressure Hg lamp, afforded the oxazolinone (2) as the major product and at least two unidentified minor components. The oxazolinone (2) has been found in soil studies as described below and is a product of rearrangement formed via an aziridinone intermediate as shown in Scheme 1 (Nakagawa et al., 1974).
Hymexazol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
View Lastest Price from Hymexazol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-08 | 3-hydroxy-5-methylisoxazole
10004-44-1
|
US $0.00 / kg | 1kg | 98.00% | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-08-30 | Hymexazol
10004-44-1
|
US $100.00 / KG | 1KG | 99% | 5000KG | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-03-06 | Hymexazol
10004-44-1
|
US $10.50 / KG | 1KG | 99% | 10 ton | Hebei Guanlang Biotechnology Co,.LTD |
-
- 3-hydroxy-5-methylisoxazole
10004-44-1
- US $0.00 / kg
- 98.00%
- Hebei Yanxi Chemical Co., Ltd.
-
- Hymexazol
10004-44-1
- US $100.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Hymexazol
10004-44-1
- US $10.50 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
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