D(-)-Arginine
- CAS No.
- 157-06-2
- Chemical Name:
- D(-)-Arginine
- Synonyms
- D-ARGININE;H-D-ARG-OH;D-ARG;D-Arg-OH;D-Arginin;H-D-Arginine;ARGININE, D-;R-(-)-ARGININE;D-(-)-ARGININE;D-Arginine，98%
- CBNumber:
- CB2408147
- Molecular Formula:
- C6H14N4O2
- Molecular Weight:
- 174.2
- MDL Number:
- MFCD00063116
- MOL File:
- 157-06-2.mol
- MSDS File:
- SDS
| Melting point | 226 °C (dec.) (lit.) |
|---|---|
| alpha | -28.5 º (c=8, 6 N HCl) |
| Boiling point | 305.18°C (rough estimate) |
| Density | 1.2297 (rough estimate) |
| refractive index | -23 ° (C=8, 6mol/L HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.49±0.24(Predicted) |
| color | White to Off-White |
| Water Solubility | SOLUBLE |
| Sensitive | Air Sensitive |
| BRN | 1725412 |
| InChIKey | ODKSFYDXXFIFQN-SCSAIBSYSA-N |
| LogP | -0.999 (est) |
| CAS DataBase Reference | 157-06-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | R54Z304Z7C |
| EPA Substance Registry System | D-Arginine (157-06-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280i-P337+P313-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CF1934220 | |||||||||
| F | 9 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29252000 | |||||||||
| NFPA 704 |
|
D(-)-Arginine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 1g | $106 | 2024-03-01 | Buy |
| Sigma-Aldrich | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 5g | $364 | 2024-03-01 | Buy |
| TCI Chemical | A1029 | D-(-)-Arginine >98.0%(T) | 157-06-2 | 1g | $57 | 2024-03-01 | Buy |
| TCI Chemical | A1029 | D-(-)-Arginine >98.0%(T) | 157-06-2 | 5g | $196 | 2024-03-01 | Buy |
| Alfa Aesar | A16137 | D-Arginine, 98% | 157-06-2 | 1g | $61.65 | 2024-03-01 | Buy |
D(-)-Arginine Chemical Properties,Uses,Production
Description
D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine.
Chemical Properties
white to light yellow crystal powde
Uses
1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine.
Uses
Arginine is an essential amino acid found in food and plant sources, and many biological systems.
D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man.
D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite.
Definition
ChEBI: A D-alpha-amino acid that is the D-isomer of arginine.
References
https://www.alfa.com/zh-cn/catalog/A16137/
Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993.
Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008).
Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.
D(-)-Arginine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
View Lastest Price from D(-)-Arginine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-26 | D(-)-Arginine
157-06-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-08-02 | D(-)-Arginine
157-06-2
|
US $0.00-0.00 / kg | 1kg | 0.99 | 500000kg | Hebei Kingfiner Technology Development Co. , Ltd. | |
 |
2021-11-02 | D(-)-Arginine
157-06-2
|
US $475.00 / KG | 1KG | 99 | 10t | Baoji Guokang Healthchem co.,ltd |
-
- D(-)-Arginine
157-06-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- D(-)-Arginine
157-06-2
- US $0.00-0.00 / kg
- 0.99
- Hebei Kingfiner Technology Development Co. , Ltd.
-
- D(-)-Arginine
157-06-2
- US $475.00 / KG
- 99
- Baoji Guokang Healthchem co.,ltd
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