2-Methylbenzimidazole
- CAS No.
- 615-15-6
- Chemical Name:
- 2-Methylbenzimidazole
- Synonyms
- 2-METHYL-1H-BENZO[D]IMIDAZOLE;2-methyl-benzimidazol;MethylbenziMidazole;1H-Benzimidazole, 2-methyl-;AKOS 90363;RARECHEM AQ NN 0067;2-METHYLENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;Methyl-2-benzimidazole;1H-2-Methylbenzimidazol
- CBNumber:
- CB5439553
- Molecular Formula:
- C8H8N2
- Molecular Weight:
- 132.16
- MDL Number:
- MFCD00005598
- MOL File:
- 615-15-6.mol
- MSDS File:
- SDS
Melting point | 175-177 °C (lit.) |
---|---|
Boiling point | 234.08°C (rough estimate) |
Density | 1.1083 (rough estimate) |
refractive index | 1.6013 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Crystalline Powder |
pka | 6.19(at 25℃) |
color | Light beige to brown |
Water Solubility | slightly soluble |
BRN | 112264 |
InChIKey | LDZYRENCLPUXAX-UHFFFAOYSA-N |
CAS DataBase Reference | 615-15-6(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | ZH8IWW7Y8B |
NIST Chemistry Reference | 1H-benzimidazole, 2-methyl-(615-15-6) |
EPA Substance Registry System | 1H-Benzimidazole, 2-methyl- (615-15-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H302-H315-H318-H335 | |||||||||
Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-37/38-41-20/21/22 | |||||||||
Safety Statements | 26-39-45-44 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DD9100000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29339990 | |||||||||
NFPA 704 |
|
2-Methylbenzimidazole price More Price(29)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | M29800 | 2-Methylbenzimidazole 98% | 615-15-6 | 5g | $36.4 | 2024-03-01 | Buy |
Sigma-Aldrich | M29800 | 2-Methylbenzimidazole 98% | 615-15-6 | 100g | $133 | 2024-03-01 | Buy |
TCI Chemical | M0286 | 2-Methylbenzimidazole >98.0%(GC)(T) | 615-15-6 | 25g | $26 | 2024-03-01 | Buy |
TCI Chemical | M0286 | 2-Methylbenzimidazole >98.0%(GC)(T) | 615-15-6 | 250g | $144 | 2024-03-01 | Buy |
Alfa Aesar | A17290 | 2-Methylbenzimidazole, 98% | 615-15-6 | 50g | $35.65 | 2024-03-01 | Buy |
2-Methylbenzimidazole Chemical Properties,Uses,Production
Chemical Properties
light beige to brown crystalline powder. Soluble in alcohol, ether, hot water and sodium hydroxide solution, insoluble in benzene.
Uses
- 2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
- It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
- It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
- 2-Methylbenzimidazole also exhibits corrosion inhibition.
Definition
ChEBI: 2-Methyl-1H-benzo[d]imidazole is a member of benzimidazoles.
Preparation
2-Methylbenzimidazole is synthesized by the condensation of o-phenylenediamine with acetic acid. The mixture of o-phenylenediamine and acetic acid is heated at 100°C for 2 hours and then cooled slowly. 10% sodium hydroxide solution is added slowly to the mixture until it is slightly alkaline. The mixture is filtered and washed with cold water. The crude product is then recrystallized with water and decolorized with activated charcoal to obtain the final product. The yield is 68%.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 1163, 1989 DOI: 10.1002/jhet.5570260447
Chemical and Pharmaceutical Bulletin, 17, p. 1153, 1969 DOI: 10.1248/cpb.17.1153
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
2-Methylbenzimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Wuhan Chemwonders Technology Inc. | 027-85778276 | info@chemwonders.com | CHINA | 176 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-15319487004 | 1015@dideu.com | China | 2132 | 58 |
View Lastest Price from 2-Methylbenzimidazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2024-09-23 | 2-Methylbenzimidazole
615-15-6
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | |
![]() |
2023-09-11 | 2-Methylbenzimidazole
615-15-6
|
US $100.00 / bag | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD | |
![]() |
2023-09-08 | 2-Methylbenzimidazole
615-15-6
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- 2-Methylbenzimidazole
615-15-6
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
-
- 2-Methylbenzimidazole
615-15-6
- US $100.00 / bag
- 99
- Hebei Fengqiang Trading Co., LTD
-
- 2-Methylbenzimidazole
615-15-6
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd