Octopamine
- CAS No.
- 104-14-3
- Chemical Name:
- Octopamine
- Synonyms
- p-Octopamine;Norden;OctopaMine-d3;ND-50;ND 50;C04227;Analet;Norfen;Norphen;OCTOPAMINE
- CBNumber:
- CB8482020
- Molecular Formula:
- C8H11NO2
- Molecular Weight:
- 153.18
- MDL Number:
- MFCD00044589
- MOL File:
- 104-14-3.mol
- MSDS File:
- SDS
Melting point | 157-158 °C |
---|---|
Boiling point | 276.1°C (rough estimate) |
Density | 1.1577 (rough estimate) |
refractive index | 1.5010 (estimate) |
solubility | Water (Easy) |
pka | pKa 8.88 (Uncertain);9.53 (Uncertain) |
optical activity | D -56.025 (0.1 mol dm-3 HCl) |
CAS DataBase Reference | 104-14-3(CAS DataBase Reference) |
EWG's Food Scores | 1-3 |
FDA UNII | 14O50WS8JD |
ATC code | C01CA18 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H312 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501 |
RIDADR | 3249 |
HazardClass | 6.1(b) |
PackingGroup | III |
Toxicity | LD50 oral in rat: 1240mg/kg |
Octopamine price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | 461480 | Octopamine | 104-14-3 | 250mg | $496 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008679 | DL-OCTOPAMINE 95.00% | 104-14-3 | 0.5G | $271 | 2021-12-16 | Buy |
AHH | MT-39562 | 4-(2-Amino-1-hydroxy-ethyl)phenol 98% | 104-14-3 | 1000g | $680 | 2021-12-16 | Buy |
Octopamine Chemical Properties,Uses,Production
Description
An alkaloid found in annual rye grass, this base has been suggested as a possible precursor of annuloline (q.v.).
Originator
Norfen,Morishita, Japan ,1975
Uses
Octopamine is a biogenic monoamine structurally related to Noradrenaline (N661038), it acts as a neurohormone, neuromodulator and a neurotransmitter in invertebrates.
Definition
ChEBI: Octopamine is a member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates. It has a role as a neurotransmitter. It is a member of phenylethanolamines and a member of tyramines. It is a conjugate base of an octopaminium.
Manufacturing Process
A solution of 33 grams of anhydrous aluminum chloride in 60 grams of nitrobenzene, to which a mixture of 14 grams of phenol and 9.3 grams of hydrochloride of amino-acetonitrile was added, had dry hydrochloric acid gas introduced into it for 3 hours, while stirring and cooling to keep the temperature between 20° and 30°C. The reaction mixture was then poured, with cooling, into 70 cc of water and the deposit obtained was sucked off, washed with acetone and dissolved in 300 cc of water. The solution thus prepared was decolorized with carbon, 50 grams of 30% sodium citrate solution was added to it, and then it was made slightly alkaline with ammonia. Thereupon hydroxy-4'-phenyl-1-amino-2-ethanone crystallized out in the form of leaflets. The yield was 7.7 grams.
The hydrochloride of this base, obtained by evaporation to dryness of a solution of the base in dilute hydrochloric acid and subsequent treatment of the residue with ethyl alcohol and acetone, had a chlorine content of 18.84%, (calculated, 18.90%).
This hydrochloride, on being dissolved in water and hydrogenated with hydrogen and a nickel catalyst, gave a good yield of hydrochloride of hydroxy4'-phenyl-1-amino-2-ethanol melting, after crystallization from a mixture of ethyl alcohol and butanone-2, at from 177° to 179°C with decomposition
Therapeutic Function
Hypertensive
References
Hardwick, Axelrod, Plant Physiol., 44, 1745 (1969)
Octopamine Preparation Products And Raw materials
Raw materials
Preparation Products
Octopamine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29823 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
Wuhan Han Sheng New Material Technology Co.,Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2118 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | 3684455296@qq.com | China | 9311 | 58 |
Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
Related articles
- Synthesis and Biological functions of Octopamine
- Octopamine plays important roles as a neurotransmitter and hormone in invertebrates.
- Jun 23,2022
View Lastest Price from Octopamine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-09-11 | Octopamine
104-14-3
|
US $100.00 / bag | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD | ||
2023-06-10 | Octopamine
104-14-3
|
US $150.00 / kg | 1kg | 99.9% | 10000MT | Henan Bao Enluo International TradeCo.,LTD | ||
2020-02-12 | Octopamine
104-14-3
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
- Octopamine
104-14-3
- US $100.00 / bag
- 99
- Hebei Fengqiang Trading Co., LTD
- Octopamine
104-14-3
- US $150.00 / kg
- 99.9%
- Henan Bao Enluo International TradeCo.,LTD
- Octopamine
104-14-3
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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