- KRN7000
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- $0.00 / 10G
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2024-03-25
- CAS:158021-47-7
- Min. Order: 1G
- Purity: 98%
- Supply Ability: kgs
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| | KRN7000 Basic information |
| | KRN7000 Chemical Properties |
| Melting point | 125-130°C | | Boiling point | 939.8±65.0 °C(Predicted) | | density | 1.04±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Pyridine (Slightly, Heated) | | form | White solid. | | pka | 12.92±0.70(Predicted) | | color | White to Pale Beige | | Stability: | Hygroscopic | | CAS DataBase Reference | 158021-47-7 |
| WGK Germany | 3 | | HS Code | 2940.00.6000 |
| | KRN7000 Usage And Synthesis |
| Description | KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis. | | Chemical Properties | White Solid | | Uses | Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. | | Uses | KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis. | | Definition | ChEBI: A glycophytoceramide having an alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. | | storage | -20°C |
| | KRN7000 Preparation Products And Raw materials |
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