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Torasemide

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Products Intro: Product Name:N-(isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
CAS:56211-40-6
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shanghai Boyle Chemical Co., Ltd.  
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Products Intro:Product Name:Torasemide
CAS:56211-40-6
Company Name: J & K SCIENTIFIC LTD.  
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Products Intro:Product Name:TorseMide
CAS:56211-40-6
Purity:98.0%(LC&T) Package:1G,5G
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
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Products Intro:Product Name:TorseMide
CAS:56211-40-6
Purity:>98.0%(LC)(T) Package:1g;5g Remarks:T2538
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
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Products Intro:Product Name:ToraseMide
CAS:56211-40-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Torasemide Basic information
Diuretics Uses
Product Name:Torasemide
Synonyms:TorseMide(DeMadex);TorseMide API;N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide Torasemide;TroseMide;Torasemide Tables;N-[(isopropylamino)carbonyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide;AC-4464;1-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonyl-3-propan-2-yl-urea
CAS:56211-40-6
MF:C16H20N4O3S
MW:348.42
EINECS:200-659-6
Product Categories:ANTIZOL;Active Pharmaceutical Ingredients;Diuretic;APIs;Torasemide;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Ion transporter and other ion channel
Mol File:56211-40-6.mol
Torasemide Structure
Torasemide Chemical Properties
Melting point 163-164°C
storage temp. -20°C Freezer
solubility DMSO: soluble18mg/mL
Water Solubility Soluble
Merck 9552
CAS DataBase Reference56211-40-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36-36/37/38
Safety Statements 26-37/39
RTECS UT7938000
MSDS Information
ProviderLanguage
Torasemide English
Torasemide Usage And Synthesis
DiureticsDiuretics are drugs mainly acting on the kidneys to increase the excretion of water and electrolytes, and increase urine output. Their potency can be divided into:
1. potent diuretics (loop diuretics): including furosemide, bumetanide, ethacrynic acid.
2. Middle efficiency diuretics include: thiazide diuretics, such as hydrochlorothiazide, bendroflumethiazide and so on.
3. Inefficient diuretics include: retention of potassium diuretics spironolactone, triamterene and carbonic anhydrase inhibitor acetazolamide and the like.
Potent diuretics effect on medullary loop ramus crude segment medulla,they inhibit reabsorption of active chlorine, followed by inhibiting sodium reabsorption, and play a strong diuretic effect.
Torasemide is a potent diuretic, its mechanism of action is similar to furosemide, it has no effect on the proximal tubules, it does not cause an increase in the discharge of potassium. This product increase renal volume and sodium excretion is dose-dependent , it does not affect the calcium and potassium excretion, excretion and metabolism have no association with renal function, large doses have no significant toxicity. Sort diuretic strength by: bumetanide> torasemide> piretanide> furosemide. It is useful in the treatment of acute and chronic renal failure and essential hypertension. Adverse reactions of torasemide are similar to furosemide ,common adverse reactions are headache, dizziness, weakness, nausea, muscle spasms, but it produces lesser extent of potassium loss ,it has no effect on uric acid, blood glucose and lipid .
The above information is edited by the chemicalbook of Tian Ye.
UsesIt is used as a diuretic.
Chemical PropertiesCrystalline Solid
Usesalcohol dehydrogenase inhibitor, antidote
UsesUsed as a diuretic
DefinitionChEBI: An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea.
Torasemide Preparation Products And Raw materials
Tag:Torasemide(56211-40-6) Related Product Information
TORASEMIDE FOR SYSTEM SUITABILITY TORSEMIDE RELATED COMPOUND B (75 MG) (N-[(N-BUTYLAMINO)CARBONYL]-4-[(3-METHYLPHENYL)A-MINO]-3-PYRIDINESULFONAMIDE) TORASEMIDE ANHYDROUS Torasemide1,4-Dihydroxy-2-Butyne 4-Amino-3-pyridinesulfonamide ISO-PROPYL-D7-AMINE Torasemide intermediate,4-(3-methylphenyl)amino-3-pyridine sulfonamide (intermediate of torasemide) Torasemide p-Toluenesulfonamide GRANULAR UREA 3-Aminobenzenesulfonamide Sulfuryl chloride Benzenesulfonamide 3-Aminopyridine Urea 4-Dimethylaminopyridine Semicarbazide 2-Aminopyridine