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BOC Sciences
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Product Name:Melinamide
CAS:14417-88-0
Remarks:Melinamide, also known as AC-223 or Artes, an amide derivative of an unsaturated long-chain fatty acid, is a new hypocholesterolaemic drug, caused a substantial decrease of the enhanced intestinal ACA
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| | Melinamide Basic information |
| Product Name: | Melinamide | | Synonyms: | Melinamide;9,12-Octadecadienamide, N-(1-phenylethyl)-, (9Z,12Z)- (9CI);9,12-Octadecadienamide, N-(1-phenylethyl)-, (Z,Z)-;AC 223;DL-a-Methylbenzyl linoleamide;DL-N-(a-Methylbenzyl)linoleamide;Linoleamide, N-(a-methylbenzyl)- (8CI);N-(a-Methylbenzyl)linoleamide | | CAS: | 14417-88-0 | | MF: | C26H41NO | | MW: | 383.61 | | EINECS: | | | Product Categories: | | | Mol File: | 14417-88-0.mol |  |
| | Melinamide Chemical Properties |
| Melting point | <4° | | Boiling point | bp0.03 200-215°; bp0.07 200-204° | | density | 0.928±0.06 g/cm3(Predicted) | | refractive index | nD23 1.5050; nD30 1.4863 | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 15.56±0.46(Predicted) | | CAS DataBase Reference | 14417-88-0 |
| | Melinamide Usage And Synthesis |
| Description | Melinamide is an amide of linoleic acid useful in the treatment of
hypercholesterolemia. The mechanism of action of melinamide appears to involve
the inhibition of cholesterol absorption from the gastrointestinal tract. | | Originator | Sumitomo (Japan) | | Uses | Melinamide is used in the synthesis and biological screening of library of macamides as TNF alpha inhibitors with greater anti-inflammatory activity in human monocytic cell. | | Definition | ChEBI: Melinamide is an organic molecular entity. | | Brand name | ARTES OIL | | Hazard | Low toxicity by ingestion. |
| | Melinamide Preparation Products And Raw materials |
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