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Oseltamivir phosphate

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Oseltamivir phosphate Basic information
Anti-influenza virus Uses
Product Name:Oseltamivir phosphate
Synonyms:ethyl (3r,4r,5s)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate phosphate;OSELTAMIVIR PHOSPHATE;NTERMEDIATES OF OSELTAMIVIR;Osteltamivir phosphate;(3R,5S)-ethyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate phosphate;Oseltamivir phosphat;Oseltamivir Phosphate (200 mg);Oselt
CAS:204255-11-8
MF:C16H31N2O8P
MW:410.4
EINECS:
Product Categories:API;Intermediates & Fine Chemicals;Pharmaceuticals;Ring Systems;Oseltamivir;Influenza Viruses;Amines;Anti-virals;apis;Tamiflu
Mol File:204255-11-8.mol
Oseltamivir phosphate Structure
Oseltamivir phosphate Chemical Properties
mp 196-198°C
storage temp. -20°C Freezer
CAS DataBase Reference204255-11-8(CAS DataBase Reference)
Safety Information
HazardClass IRRITANT
MSDS Information
Oseltamivir phosphate Usage And Synthesis
Anti-influenza virusOseltamivir phosphate is a kind of anti-influenza drugs, under the trade name Tamiflu. Its appearance exhibits as white to yellowish-white powder. It can be divided into type A (alpha) and B (Beta) selective inhibitor of the influenza virus neuraminidase and can prevent the release of virus from infected cells, through inhibiting the activity of the influenza virus neuraminidase, thus achieving the purpose of control of influenza symptoms. Clinically it can be used for treatment of the type A influenza and type B influenza in adults and children of 1 year old or over 1 year old as well as the clinical prevention of influenza A and B in adult and adolescent of 13 year old or over 13 years old.
Oseltamivir phosphate can subject to rapid metabolism into oselatamivr carboxylate after gastrointestinal absorption with 75% of the total oral administrated dose participating in the systemic circulation in the from of oselatamivr carboxylate. The active ingredient of this drug is a potent and unique neuraminidase inhibitors acting on all the processes of influenza virus infection, preventing the replication of all clinically relevant influenza virus strains A or B strain. It has obvious inhibitory effect even in nanomolar concentration in vitro. It has ben observed in vitro that the active metabolite can inhibit the growth of influenza virus as well as in vivo that it can inhibit the replication and pathogenicity of influenza virus. This product, through inhibiting the release of virus from infected cells, can reduce the spread of influenza A or B virus.
The above information is edited by the chemicalbook of Dai Xiongfeng.
UsesAntibiotics and anti-virus
Chemical PropertiesWhite Cyrstalline Solid
UsageOrally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug.
UsageOseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective; however, once in the liver, it is converted by natural chemical processes, hydrolysed hepatically to its
UsageAn antiviral agent
Oseltamivir phosphate Preparation Products And Raw materials
Tag:Oseltamivir phosphate(204255-11-8) Related Product Information
2-Cyclohexen-1-one AMPHISOL A 4-Acetamidophenol Ethyl formate Ethylparaben Pentane Cyclohexene Acetamide Zinc phosphate Tylosin phosphate Thioacetamide N,N-Dimethylacetamide ROCK PHOSPHATE Cyclohexene oxide EC 3.1.3.1 Triethyl phosphate Pentasodium triphosphate hexhydrate ISOXADIFEN-ETHYL