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| | illudin M Basic information |
| Product Name: | illudin M | | Synonyms: | illudin M;(3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one;(3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one;Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)- | | CAS: | 1146-04-9 | | MF: | C15H20O3 | | MW: | 248.32 | | EINECS: | | | Product Categories: | ADC | | Mol File: | 1146-04-9.mol |  |
| | illudin M Chemical Properties |
| Melting point | 120-122.5° (Matsumoto); mp 128-130° (McMorris) | | Boiling point | 452.4±45.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble | | form | A solid | | pka | 12.57±0.70(Predicted) |
| | illudin M Usage And Synthesis |
| Description | Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies. | | Uses | Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication. | | Definition | ChEBI: Illudin M is a sesquiterpenoid. |
| | illudin M Preparation Products And Raw materials |
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