ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Pituitary hormone drugs >Mifepristone


Mifepristone Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:Mifepristone
Purity:99% Package:5940/KG
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd.
Tel: +86-10-60279497 +86(0)15646567669
Products Intro: Product Name:Mifepristone
Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:84371-65-3
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
Tel: 025-83697070;
Products Intro: CAS:84371-65-3
Purity:98% Package:g-Kg Remarks:Light yellow crystalline powder
Company Name: Nanjing Finetech Chemical Co., Ltd.
Tel: 025-85710122 17714198479
Products Intro: CAS:84371-65-3
Purity:99%min Package:1KG;10KG;100KG;500KG;100g Remarks:ISO certified
Mifepristone Basic information
Product Name:Mifepristone
Product Categories:Steroids;Hormone;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Nuclear Receptors;Steroid and Hormone;API;Hormone Drugs
Mol File:84371-65-3.mol
Mifepristone Structure
Mifepristone Chemical Properties
Melting point 195-198°C
alpha D20 +138.5° (c = 0.5 in chloroform)
storage temp. 2-8°C
Merck 14,6186
CAS DataBase Reference84371-65-3(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 60-61
Safety Statements 53-22-36/37/39-45
WGK Germany 3
RTECS KG2955000
Hazardous Substances Data84371-65-3(Hazardous Substances Data)
Mifepristone Usage And Synthesis
DescriptionMifepristone is a kind of antagonist of the progestational and glucocorticoid hormone. It is mainly used for the treatment of hypercortisolism in patients with nonpituitary cushing syndrome. During the treatment of Cushing’s syndrome, mifepristone takes effect through interfering with the binding of cortisol to its receptor. It reduces the effects of excess cortisol (e.g., high blood sugar levels) without causing decreased cortisol production. It can also be used to end a pregnancy. Its inhibition on progesterone can induce bleeding during the luteal phase and in early pregnancy.  
Chemical PropertiesPale Yellow Solid
Usesglutamate uptake inhibitor, AMPA blocker
UsesA progesterone and glucocorticoid antagonist, suppresses VEGF production.
UsesA progesterone receptor antagonist with partial agonist activity. Abortifacient.
Biological ActivitySelective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitro and in vivo . Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone.
Mifepristone Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->N,N-Dimethylaniline-->Isopropyl ether-->Dimethyl sulfide
Tag:Mifepristone(84371-65-3) Related Product Information
mifepristone methochloride N-DESMETHYL MIFEPRISTONE,N-Demethyl Mifepristone Mifepristone(RU486) Didemethyl Mifepristone,DIDESMETHYL MIFEPRISTONE,N-Didesmethyl Mifepristone Mifepristone-d3 22-Hydroxy Mifepristone-d6 Estr-9-en-3-one, 11-[4-(dimethylamino)phenyl]-5,17-dihydroxy-17-(1-propynyl)-, cyclic 1,2-ethanediyl acetal, (5a,11b,17b)- RU486 (Mifepristone) Mifepristone,Methandrostenolone Toripristone MIFEPRISTONE, [N-METHYL-3H] RU-486 (MIFEPRISTONE), [N-METHYL-3H] HYDROXY MIFEPRISTONE,22-Hydroxy Mifepristone Mifepristone CHLOROPHOSPHONAZO III Phenylhydrazine PHENYL VALERATE