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Mifepristone

Mifepristone Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Mifepristone
CAS:84371-65-3
Purity:99% Package:5940/KG
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd.
Tel: +86-10-60279497 +86(0)15646567669
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:Mifepristone
CAS:84371-65-3
Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Nanjing Sunlida Biological Technology Co., Ltd.  Gold
Tel:025-58378339;025-57798810
Email:sales@sunlidabio.com
Products Intro:Product Name:Mifepristone
CAS:84371-65-3
Purity:98.5% Remarks:SLD-2342
Company Name: Wuhan HengWo Technology Co., Ltd.  Gold
Tel:0571-87963082 18062502932
Email:chemicala@163.com
Products Intro:Product Name:Mifepristone
CAS:84371-65-3
Purity:99%
Company Name: Nanjing Banguo Biological Technology Co., Ltd  Gold
Tel:025-52102322 17327091946
Email:q2355935195@ycphar.com
Products Intro:CAS:84371-65-3
Purity:99%
Mifepristone Basic information
Description
Product Name:Mifepristone
Synonyms:11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486
CAS:84371-65-3
MF:C29H35NO2
MW:429.59
EINECS:
Product Categories:Steroids;Hormone;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Nuclear Receptors;Steroid and Hormone;API;Hormone Drugs
Mol File:84371-65-3.mol
Mifepristone Structure
Mifepristone Chemical Properties
Melting point 195-198°C
storage temp. 2-8°C
Merck 6186
CAS DataBase Reference84371-65-3(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 60-61
Safety Statements 53-22-36/37/39-45
WGK Germany 3
RTECS KG2955000
Hazardous Substances Data84371-65-3(Hazardous Substances Data)
Mifepristone Usage And Synthesis
DescriptionMifepristone is a kind of antagonist of the progestational and glucocorticoid hormone. It is mainly used for the treatment of hypercortisolism in patients with nonpituitary cushing syndrome. During the treatment of Cushing’s syndrome, mifepristone takes effect through interfering with the binding of cortisol to its receptor. It reduces the effects of excess cortisol (e.g., high blood sugar levels) without causing decreased cortisol production. It can also be used to end a pregnancy. Its inhibition on progesterone can induce bleeding during the luteal phase and in early pregnancy.  
Chemical PropertiesPale Yellow Solid
Usesglutamate uptake inhibitor, AMPA blocker
UsesA progesterone and glucocorticoid antagonist, suppresses VEGF production.
UsesA progesterone receptor antagonist with partial agonist activity. Abortifacient.
Biological ActivitySelective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitro and in vivo . Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone.
Referenceshttps://pubchem.ncbi.nlm.nih.gov/compound/mifepristone#section=Top
https://www.drugbank.ca/drugs/DB00834
https://www.drugs.com/cdi/mifepristone-tablets.html
Mifepristone Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->N,N-Dimethylaniline-->Isopropyl ether-->Dimethyl sulfide
Tag:Mifepristone(84371-65-3) Related Product Information
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