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L-Leucine

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Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:(S)-2-amino-4-methylpentanoic acid
CAS:61-90-5
Purity:98%(Min) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
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Products Intro: Product Name:L-Leucine
CAS:61-90-5
Purity:98% Package:77/KG
Company Name: Emeishan Longteng Biotechnology Co., Ltd,   Gold
Tel:028-83312894 13808028560
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Products Intro:Product Name:61-90-5
CAS:61-90-5
Purity:98.5%
Company Name: Shanghai Xilong Biochemical Technology Co., Ltd.  Gold
Tel:021-52907766-8042
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Products Intro:CAS:61-90-5
Purity:99% Package:45RMB/25g
Company Name: Shanghai Boyle Chemical Co., Ltd.  
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Email:sales@boylechem.com
Products Intro:Product Name:L-Leucine
CAS:61-90-5
L-Leucine Basic information
description Chemical Properties Uses toxicity
Product Name:L-Leucine
Synonyms:(s)-2-amino-4-methylvalericacid;1-Leucine;2-Amino-4-methylpentanoic acid;2-amino-4-methylpentanoicacid;2-amino-4-methyl-valericaci;4-methyl-l-norvalin;4-methyl-norvalin;alpha-Amino-gamma-methylvaleric acid
CAS:61-90-5
MF:C6H13NO2
MW:131.17
EINECS:200-522-0
Product Categories:Food and Feed Additive;Amino Acid Derivatives;Leucine [Leu, L];Amino Acids;Amino Acids and Derivatives;alpha-Amino Acids;Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids;amino
Mol File:61-90-5.mol
L-Leucine Structure
L-Leucine Chemical Properties
Melting point >300 °C(lit.)
alpha 15.4 º (c=4, 6N HCl)
density 1,293 g/cm3
FEMA 3297
Fp 145-148°C
storage temp. Store at RT.
solubility 1 M HCl: 50 mg/mL
form powder
pka2.328(at 25℃)
color White to Off-white
PH5.5-6.5 (20g/l, H2O, 20℃)
Water Solubility 22.4 g/L (20 C)
Sublimation 145-148 ºC
Merck 14,5451
BRN 1721722
Stability:Stability Moisture and light sensitive. Incompatible with strong oxidising agents.
CAS DataBase Reference61-90-5(CAS DataBase Reference)
NIST Chemistry ReferenceLeucine(61-90-5)
EPA Substance Registry SystemL-Leucine(61-90-5)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS OH2850000
TSCA Yes
HS Code 29224995
MSDS Information
ProviderLanguage
L-Leu English
SigmaAldrich English
ACROS English
ALFA English
L-Leucine Usage And Synthesis
descriptionL-leucine is one of the eight essential amino acids, and belonging to the aliphatic amino acids within twenty kinds of proteins. L-leucine and L-isoleucine and L-valine are called three branched chain amino acids. L-leucineLeucine and D-leucine are enantiomers . It is a white shiny hexahedral crystal or white crystalline powder at room temperature , Odorless, slightly bitter . In the presence of hydrocarbons ,it is stable in the aqueous mineral acid. Per gram is dissolved in 40ml water and about 100ml acetic acid. Very slightly soluble in ethanol or ether, dissolved in formic acid, dilute hydrochloric acid, a solution of alkali hydroxides and a solution of carbonates.
L-leucine can promote insulin secretion, can lower blood sugar; promote sleep, reduce sensitivity to pain, migraine headaches, anxiety and ease tension, reduce symptoms of chemical reactions disorder in the body caused by alcohol , and helps control alcoholism; it has a role in the treatment of dizziness , also can promote skin wound and bone healing, so doctors usually advise patients to take leucine supplements after surgery. amino acid infusion and comprehensive amino acid preparations are often formulated to be used in the treatment or health care; also be used as food, cosmetics and feed additives and plant growth promoter.
The best food sources of leucine include brown rice, beans, meat, nuts, soy flour, and whole wheat. Excessive intake can also cause side effects, high intake can cause pellagra, vitamin A deficiency, dermatitis, diarrhea, mental disorders and other issues,which needs to be paid attention to . Diet containing too much leucine will increase the number of ammonia in the body and destroy the liver and kidney function. Therefore, patients with impaired liver or kidney function should not be excessive intake, otherwise it will exacerbate the condition.
Chemical PropertiesWhite shiny hexahedral crystals or white crystalline powder. Slightly bitter (DL-leucine is sweet). Sublimation at 145~148 ℃. Melting point 293~295 ℃ (decomposition). It belongs to the essential amino acids,and adult men requirement is 2.2g/d (151 version). It is necessary in normal growth for infants and maintaining normal nitrogen balance for adults.
Natural products are found in the spleen, heart, etc., and are present in a variety of plant and animal tissues in the form of the proteins, free out after decomposition and corruption.
UsesAmino acid drugs. Used as amino acid infusion and comprehensive amino acid preparations. For the diagnosis and treatment of children with idiopathic high blood sugar and glucose metabolism disorders,bile liver disease associated with reduced secretion , anemia, poisoning, muscular dystrophy, poliomyelitis, neuritis and mental illness. Diabetes, cerebral vascular sclerosis and kidney disease associated with proteinuria and hematuria is contraindicated. Gastric and duodenal ulcer patients should not be served.
The product is used as a nutritional supplement,an amino acid infusion preparation and a comprehensive amino acid preparation,a hypoglycemic agent, a plant growth promoter.The product can be used as a spice according to GB 2760-8 .
toxicitySafe for food (FDA, §172.3202000).
LD505379mg/kg (rat, subcutaneously).
Chemical PropertiesWhite crystalline powder
DefinitionChEBI: The L-enantiomer of leucine.
Tag:L-Leucine(61-90-5) Related Product Information
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