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(9R)-6'-methoxycinchonan-9-ol

(9R)-6'-methoxycinchonan-9-ol Suppliers list
Company Name: Hefei Hirisun Pharmatech Co., Ltd
Tel: +8615056975894
Email: shawn@hirisunpharm.com
Products Intro: Product Name:2,3,4,6-tetraacetate-alpha-D-Glucopyranosyl bromide
CAS:572-59-8
Purity:0.95 Package:1G;5G;25G;Bulk for inquiry Remarks:HR040048
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Email: sales@amadischem.com
Products Intro: Product Name:(9R)-6'-methoxycinchonan-9-ol
CAS:572-59-8
Purity:0.97 Package:mgs,gs,kgs Remarks:A897898
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:9-epi-Quinidine
CAS:572-59-8
Package:100Mg,1g
Company Name: Chemsky (shanghai) International Co.,Ltd  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:9-epi-Quinidine;(9R)-
CAS:572-59-8
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
Company Name: Guangzhou Isun Pharmaceutical Co., Ltd  
Tel: 020-39119399 18927568969
Email: isunpharm@qq.com
Products Intro: Product Name:Epiquinidine
CAS:572-59-8
Purity:97.0% Package:1g; 5g; 10g; 50g; 100g;
(9R)-6'-methoxycinchonan-9-ol Basic information
Product Name:(9R)-6'-methoxycinchonan-9-ol
Synonyms:Epiquindine;(9R)-6'-methoxycinchonan-9-ol;(8R,9R)-6'-Methoxycinchonan-9-ol;9-Epiquinidine;Epiquinidine;(R)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol;(R)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol;(9R)-
CAS:572-59-8
MF:C20H24N2O2
MW:324.42
EINECS:209-340-6
Product Categories:Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:572-59-8.mol
(9R)-6'-methoxycinchonan-9-ol Structure
(9R)-6'-methoxycinchonan-9-ol Chemical Properties
Melting point 111-113°
alpha D25 +107.8° (c = 1.02 in ethanol)
Boiling point 462.75°C (rough estimate)
density 1.1294 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. 2-8°C
pka12.80±0.20(Predicted)
Safety Information
Hazard Codes Xn
Risk Statements 22-42/43
Safety Statements 22-36/37-45
MSDS Information
(9R)-6'-methoxycinchonan-9-ol Usage And Synthesis
DescriptionThis alkaloid is stereoisomeric with epiQuinine and occurs in 'Quinoidine', the mixture of amorphous bases left after extraction of the four primary alkaloids of Cinchona bark. It crystallizes in colourless leaflets from Et20 and is fluorescent in dilute H2S04, It is dextrorotatory with [α]19D + 102.4° (c 0.8648, EtOH) and furnishes a dihydrochloride, m.p. 195-6°C (dec.); [α]20D + 45.5° (c 0.8012, EtOH); a hydrobromide, m.p. 240°C; thiocyanate, m.p. 193°C; [α]20D + 44.5° (H20) and the dibenzoyl-(+)-tartrate, m.p. 167°C; [α]201D + 3.7° (c 0.8068, EtOH-CHCI 3 ). Catalytic hydrogenation with Pd gives the dihydro derivative, m.p. 122°C; [α]22D + 73.1° (c 0.766, EtOH).
UsesThe 9-epimer of Quinidine (Q685000). Antimalarial.
ReferencesThron, Dirscherl., Annalen, 521,48 (1935)
(9R)-6'-methoxycinchonan-9-ol Preparation Products And Raw materials
Tag:(9R)-6'-methoxycinchonan-9-ol(572-59-8) Related Product Information
Quinine