The Application and Synthesis of 3-Acetylpyridine
3-Acetylpyridine is a pyridine derivative and it is primarily used as a raw material or intermediate for synthesizing various therapeutic drugs In the pharmaceutical field.
Oct 28，2025 Amides
Loperamide Hydrochloride: Therapeutic Antidiarrheal Use and Abuse Risks
Loperamide hydrochloride is an over-the-counter antidiarrheal , while high-dose abuse causes CNS issues and severe cardiotoxicity like QTc prolongation.
Oct 27，2025 API
Megestrol Acetate: Anticancer Mechanisms and CYP3A4 Induction
Megestrol acetate induces endometrial cancer cell senescence (PR-B/FOXO1/p21 axis), relieves CINV, but activates hPXR to induce CYP3A4.
Oct 27，2025 API
Isobutaneboronic Acid: Residual Solvent Determination & Derivatization
Isobutaneboronic acid uses DAN-derivatization to avoid GC column damage, enabling accurate residual solvent detection per ICH guidelines.
Oct 27，2025 API
Ethyl S-4-Chloro-3-Hydroxybutyrate: Bioreduction Synthesis & Production Enhancement
Ethyl S-4-chloro-3-hydroxybutyrate is synthesized via COBE bioreduction (high ee >99.9%) with cofactor recycling; adsorption systems boost production.
Oct 27，2025 Chemical Reagents
Corosolic Acid: Antidiabetic Effects & Structural Analogs
Corosolic acid boosts insulin sensitivity, modulates cancer pathways (NF-κB/PI3K/Akt), and has analogs with improved bioavailability.
Oct 27，2025 API
Taurodeoxycholic Acid Sodium Salt: Chaperoning Activity & In Vivo Toxicity
Taurodeoxycholic acid sodium salt (TDCA) acts as a chemical chaperone, has low systemic toxicity, but causes injection-site lesions at ≥20 mg/kg in rats.
Oct 27，2025 Chemical Materials
Applications of 3-Chloropropyltrimethoxysilane in Surface Modification of Materials
3-Chloropropyltrimethoxysilane enables surface functionalization, enhancing material stability, adsorption, membrane formation, and composite flame retardancy.
Oct 24，2025 Organic Chemistry
The use of Deslorelin in different animals
Deslorelin is a synthetic gonadotropin-releasing hormone (GnRH) agonist that is seven times more potent than GnRH. Its use in animals were reported here.
Oct 24，2025 Drugs
Application research of D-2-phenylglycine
As an important pharmaceutical intermediate and an important raw material for cephalosporin antibiotics, D-2-Phenylglycine has broad application prospects.
Oct 24，2025 Organic Synthesis Intermediate