What is the relationship between Uracil and Uracil-DNA glycosylase?
Uracil is an important component of RNA and is closely related to the transmission of genetic traits. Uracil can be used to repair and select large-scale DNA sequence deletions.
Dec 16，2024 Biochemical Engineering
Triethyl Citrate: Applications in Boosting PLA/Chitin Nanocomposites and its Toxicity Summary
Triethyl citrate improves PLA/Chitin nanocomposites' properties while raising safety concerns due to varied toxicity responses in animal studies, despite low irritation potential in humans.
Dec 16，2024 API
Biological functions of cyclic AMP in different tissues
Cyclic AMP, also known as cyclic adenosine monophosphate (3′,5′-cyclic AMP or cAMP for short), is a cyclic nucleotide used as a second messenger for intracellular signal transduction in prokaryotes an
Dec 16，2024 Amino Acids and Derivatives
What is Eribulin Mesylate liposome?
Eribulin Mesylate liposome is a drug delivery form of Eribulin Mesylate.
Dec 16，2024 Drugs
Teneligliptin: Indications, Mechanism of Action and Side Effects
Teneligliptin is a novel third-generation DPP-4 inhibitor approved for the treatment of type II diabetes. The compound has a unique five-continuous ring structure that produces a potent and long-lasti
Dec 16，2024 Drugs
Preparation of Cytidine 5'-Diphosphocholine
Cytidine 5'-Diphosphocholine (Citicoline, CDP-choline) is a mononucleotide composed of ribose, cytosine, pyrophosphate and choline, and is a naturally occurring endogenous compound.
Dec 16，2024 Biochemical Engineering
What is the use of MOTS-c? And what diseases may be associated with its reduced levels?
MOTS-c is one of the mitochondrial-derived peptides, which has the effects of promoting fatty acid oxidation, promoting white fat browning, enhancing glucose utilization, improving insulin resistance,
Dec 16，2024 Biochemical Engineering
Is baloxavir marboxil safe for oral administration?
Yes. Baloxavir marboxil is well tolerated as a single oral dose, has a favorable safety profile, and has a favorable pharmacokinetic profile, including a long half-life (49-91 hours), supporting singl
Dec 16，2024 Drugs
Trabectedin indications, mechanism of action and side effects
Trabectedin is an antineoplastic drug approved by the EMA for the treatment of soft tissue sarcoma (STS).
Dec 16，2024 Drugs
Camptothecin vs. 10-Hydroxycamptothecin: Uses and Synthesis
Camptothecin (CPT) is a pentacyclic natural alkaloid extracted from Camptotheca acuminata. CPT is a unique class of complex quinoline cytotoxins that inhibit the DNA enzyme topoisomerase I (topo I).
Dec 16，2024 Plant extracts