D-Threonine VS L-Threonine

D-threonine is one of the essential unnatural amino acids and is used as a chiral building block of peptidomimetic drugs for the treatment of peripheral opioid side effects and analgesic applications.

Mar 28,2024  Biochemical Engineering

The uses of Fmoc-Orn(Boc)-OH

Fmoc-Orn(Boc)-OH is an ornithine-containing amino acid building block. It has been used to conjugate ornithine to GFP-labeled peptides, enhancing cell permeability compared to unconjugated GFP-labeled

Mar 28,2024  Biochemical Engineering

Nitazoxanide: A Versatile Pharmacological Agent

Nizosin is a broad-spectrum antiparasitic and antiviral drug that has become an important drug since its approval in the early 21st century.

Mar 28,2024  API

Synthesis and Applications of 2,2 ', 4,4' – Tetrahydroxybenzophenone

2,2 ', 4,4' - Tetrahydroxybenzophenone is widely used in the plastic, resin, coating, synthetic rubber, photosensitive materials, and cosmetics industries.

Mar 28,2024  API

Avatrombopag Maleate: Preclinical Pharmacology, Pharmacokinetics and Metabolism

Avatrombopag maleate shows potent TPO receptor activation, selective human platelet generation, and promising pharmacokinetics, supporting its development for platelet disorders.

Mar 28,2024  API

1,5-Naphthalene diisocyanate: Preparation, Applications as a Building Block and Health Hazards

1,5-Naphthalene diisocyanate is prepared with high yield, serving as a crucial building block for high-performance polyurethane elastomers, yet posing significant health hazards.

Mar 28,2024  API

Minoxidil sulphate: History and Pharmacokinetics

Minoxidil sulphate, approved for hypertension, later found use in treating baldness due to hypertrichosis. Its absorption and metabolism inform treatment optimization.

Mar 28,2024  API

The refinement of the crystal structure of skutterudite, CoAs3

The crystal structure of skutterudite, cobalt triarsenide, has been re-refined with new data collected at 22 °C on a Picker automatic diffractometer (Mo Ke) out to a maximum sin 0/).=0.60, with the mo

Mar 27,2024  API

Regorafenib: Uses, Mechanism of Action and Side effects

Regorafenib is a targeted anticancer prescription drug that belongs to the diphenylurea class of multikinase inhibitors, targeting angiogenic receptors (VEGFR1-3, TIE2), stromal receptors (PDGFR-β, FG

Mar 27,2024  Drugs

Uranium diboride:Crystal structure,Uses,Synthesis

Uranium diboride (UB2) is a refractory ceramic with physical properties that make it a promising candidate for the development of high-performance nuclear materials, including fuel.

Mar 27,2024  Inorganic chemistry
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