Cobalt Carbonyl Complexes: Imidazol-2-ylidene Stabilization and Polymer-Supported Catalysis
Cobalt carbonyl, a key catalyst, forms stable tetrahedral complexes with imidazol-2-ylidene; polymer-supported ones catalyze Pauson–Khand reactions.
Oct 15，2025 Chemical Materials
D(+)-Phenylalaninol: Synthesis, Chiral Recognition, and Gastric Acid Secretion Inhibition
D(+)-Phenylalaninol, synthesized via Cu-catalyzed hydrogenation, aids chiral recognition and significantly inhibits centrally induced gastric acid secretion.
Oct 14，2025 Chemical Materials
Carmine: Sources and Allergy in Urticaria Patients
Carmine, from Dactylopius coccus, forms stable Cu(II) complexes; causes allergies in urticaria patients, with CC38K as main allergen.
Oct 14，2025 Dyes and Pigments
5-Phenyltetrazole: Alkylation Reactions and Key Properties
5-Phenyltetrazole undergoes ortho-hydroxybenzylation via Mannich bases (52% yield) and methylation with clear product separation.
Oct 14，2025 API
Benzyl Acrylate: Interchain Transfer Constant Determination
Benzyl acrylate, a versatile monomer, has its interchain transfer constants to PEA (1–2×10??) determined; activation energy is 47.8 kJ mol?1.
Oct 14，2025 API
Testosterone Isocaproate: Cardiovascular Links and Subcutaneous Therapy
Testosterone Isocaproate, has unique crystal packing, links to cardiovascular health, and effective subcutaneous administration for hypogonadism.
Oct 14，2025 Drugs
Application research of 4-amino-2-(trifluoromethyl)benzonitrile
4-Amino-2-(trifluoromethyl)benzonitrile is a useful pharmacophore found in the anticancer drug bicalutamide as a structural unit. Its application was summarized
Oct 14，2025 Pharmaceutical intermediates
Methyl 3-Hydroxypropanoate: Catalytic Synthesis from Ethylene Oxide and Thermolysis Behavior
Methyl 3-hydroxypropanoate is synthesized via Co-catalyzed ethylene oxide carbonylation and its thermolysis in m-xylene is favored by solvent interactions.
Oct 14，2025 API
Efficacy in Hypertension/Heart Failure and PK Insights of Nebivolol Hydrochloride
Nebivolol hydrochloride, a third-gen beta-blocker, treats hypertension/heart failure via β1-blockade and NO-mediated vasodilation.
Oct 14，2025 API
Rifamycin O: Efficacy Against M. abscessus and Overcoming Antibiotic Resistance
Rifamycin O, an RNA polymerase inhibitor, treats E. coli-induced traveler's diarrhea and shows promise against M. abscessus.
Oct 14，2025 API