Sorafenib tosylate tablets vs Sorafenib tosylate powder: Human prescription drug vs Animal drug
orafenib tosylate tablets are an oral, FDA-approved human prescription drug. It is a kinase inhibitor that contains 200 mg of sorafenib, equivalent to 274 mg of sorafenib tosylate.
Jul 30，2025 Biochemical Engineering
Nintedanib:Class, Uses, Synthesis, Mechanism of Action and Toxicity
Nintedanib was initially approved by the U.S. Food and Drug Administration (FDA) in 2014 as a treatment for idiopathic pulmonary fibrosis (IPF).
Jul 30，2025 API
Are erlotinib and gefitinib interchangeable for non-small cell lung cancer treatment?
Depends on the circumstances. Gefitinib and erlotinib are both orally active EGFR TKIs but with different structure, which means different affinity with their receptor.
Jul 30，2025 API
Abemaciclib:Drug class, Brand name, Uses and Diet recommendations
Abemaciclib blocks proteins known as CDK (cyclin dependent kinase) 4 and 6. When activity of CDK 4 and 6 is increased, there is a loss of cell cycle control that leads to increased cell growth and div
Jul 30，2025 API
Cinacalcet:Brand name, Uses, Pharmacokinetics and Precautions
Cinacalcet is a calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium.
Jul 30，2025 API
Sorafenib: An Important Option for the Treatment of Hepatocellular Carcinoma (HCC)
Sorafenib (Nexavar) was approved in the EU and the USA for use in HCC in 2007, and remains the only systemic agent approved for use in this indication.
Jul 30，2025 API
Cinacalcet hydrochloride: Uses, Synthesis and Dosage
Cinacalcet hydrochloride is the first active pharmaceutical ingredient approved by the US FDA for the treatment of secondary hyperparathyroidism.
Jul 30，2025 Biochemical Engineering
Dasatinib:Class, Uses, Advantages,Usage and Toxicity
Unlike imatinib, another tyrosine kinase used for the treatment of CML and Ph-positive ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain.
Jul 30，2025 API
BTK inhibitor Ibrutinib:Brand names,Uses,Dietary instructions and Toxicity
Ibrutinib is a small molecule with the ability to form a covalent bond with Cys-481 in the ATP binding domain of BTK. The IC50 of ibrutinib for BTK is 0.5 nM.
Jul 30，2025 API
What are the main indications for Regorafenib (Hydrochloride)?
Like fruquintinib, Regorafenib (Hydrochloride) is a small molecule tyrosine kinase inhibitor for the treatment of metastatic colorectal cancer.
Jul 29，2025 Biochemical Engineering