Trypsin in colorectal cancer
Trypsin is overexpressed in cancer and contributes to invasiveness. In colorectal cancer, trypsin overexpression correlates with poor prognosis.
Jan 24，2024 API
Sodium cocoyl isethionate: Origin, Benefits for Skin and Side Effects
Sodium cocoyl isethionate is a gentle and effective natural ingredient used in personal care products for cleansing and moisturizing the skin without causing dehydration.
Jan 24，2024 API
Biosynthesis of Pyridoxal Phosphate: A Crucial Coenzyme in Biochemical Reactions
Pyridoxal phosphate is a crucial coenzyme in biochemical reactions. It is synthesized through DXP-dependent and R5P-dependent pathways, with implications for therapeutics and health.
Jan 24，2024 API
Nicotinamide riboside chloride: biological activities and preclinical studies
Nicotinamide riboside chloride increases NAD+ levels, has similar toxicity to nicotinamide, and shows potential benefits in metabolism, liver health, and exercise performance.
Jan 24，2024 API
Effect of enteral nutrition supplemented with octanoic acid on lipopolysaccharide-induced intestinal injury
Enteral nutrition supplemented with octanoic acid prevents lipopolysaccharide-induced intestinal injury via the peroxisome proliferator-activated receptor γ/STAT-1/myeloid differentiation factor 88 pa
Jan 23，2024 Inhibitors
Is Relugolix for advanced prostate cancer FDA-approved?
Yes.The US Food and Drug Administration on 18 December 2020 approved the first oral gonadotropin-releasing hormone (GnRH) receptor antagonist, relugolix for adult patients with advanced prostate cance
Jan 23，2024 Drugs
The introduction of KPT-330(Selinexor)
Selinexor is a first-in-class, oral, small molecule Exportin-1 (XPO1) inhibitor that is being developed by Karyopharm Therapeutics for the treatment of cancer.
Jan 23，2024 Inhibitors
A FLT3 receptor tyrosine kinase inhibitor: Quizartinib dihydrochloride
uizartinib dihydrochloride, or AC220, is a highly potent oral FLT3 receptor tyrosine kinase inhibitor approved in Japan for treating patients with relapsed/refractory FLT3-ITD-positive AML.
Jan 23，2024 Inhibitors
Effect of Triton X-100 on the wheat and lettuce growth and contaminant absorption
?Triton X-100 is a surfactant used in a wide range of applications, including agriculture, but its effects on crops are unknown.
Jan 23，2024 Surfactant
Application and Mechanism of Action of Crotamiton
Crotamiton is an anti-scabies medication,Scabies is a contagious skin disease caused by the microscopic mite Sarcoptes scabiei that causes intense itching.
Jan 23，2024 Drugs