The synthesis method of Tezacaftor
Tezacaftor is a broad-acting CFTR corrector similar to lumacaftor that facilitates the cellular processing and trafficking of normal CFTR and multiple mutant CFTR forms.
Jan 3，2024 Biochemical Engineering
Structure and Polarity of 1,4-Dimethoxybenzene
The structure of 1,4-Dimethoxybenzene consists of a benzene ring and two para-position methoxy groups, it behaves as a non-polar molecule. Researchers also studied its molecular orbital study.
Jan 3，2024 Flavors and fragrances
What is Omidenepag Isopropyl
Omidenepag isopropyl (OMDI), administered as a 0.002% ophthalmic solution, was approved in Japan in 2018 for treating glaucoma and ocular hypertension.
Jan 3，2024 Biochemical Engineering
Talazoparib (BMN 673): a polymerase inhibitor
Talazoparib is a PARPi developed by Pfizer and approved in 2018 in USA and 2019 in EU for the treatment of germline BRCA-mutated, HER2-negative breast cancer.
Jan 3，2024 Inhibitors
Can nicotinamide riboside protect against cognitive impairment?
Based on recent findings, oral supplementation with nicotinamide riboside inhibits the accumulation of pathological features of Alzheimer's disease and improves learning and memory in various mouse mo
Jan 3，2024 Biochemical Engineering
Is 4-Butylresorcinol safe in the treatment of melasma?
4-Butylresorcinol 0.1% Cream has shown rapid efficacy and good tolerability when used in the treatment of melasma.
Jan 3，2024 API
How to synthesize Plitidepsin?
Plitidepsin, dehydrodidemnin B, is a macrocyclic marine natural product isolated nearly 40 years ago from the tunicate aplidium albicans.
Jan 3，2024 Biochemical Engineering
Is Selenium tetrachloride a polar molecule?
?Selenium tetrachloride is an inorganic compound composed with the formula SeCl4. This compound exists as a yellow-to-white volatile solid. It is a polar molecule.
Jan 3，2024 Inorganic salts
The Benzoin polarity and thin-layer chromatography
Benzoin, benzil, and hydrobenzoin are all compounds used in thin-layer chromatography (TLC). This technique separates and identifies components in a mixture.
Jan 3，2024 Organic Solvents
Glycerol: Uses; Side Effects and Precautions
Glycerin is FDA-approved for the treatment of constipation. The use of glycerin as a suppository or rectal enema may reduce constipation in adults and children at least 2 years of age.
Jan 3，2024 API