Side effects and toxicity of Ethylene thiourea in humans
Ethylene thiourea (ETU) is an imidazolidine compound with the appearance of a white crystalline solid, produced by the action of ethylenediamine on carbon disulphide in hydroalcohol.
Jan 18，2024 API
How to synthesize Entrectinib
Entrectinib is an orally available, CNS-active, selective inhibitor of the tyrosine kinases tropomyosin receptor kinase (Trk) A/B/C, anaplastic lymphoma kinase (ALK), and c-ros oncogene 1 (ROS1).
Jan 18，2024 Biochemical Engineering
The uses of 2',7'-Dichlorofluorescein
DCF is used directly, there is a decline in fluorescence in the presence of ROS. Hence, DCFH2-DA (not DCF) should be used to indicate ROS generation.
Jan 18，2024 Analytical Chemistry
Difelikefalin: Synthesis and Introduction
Difelikefalin is synthesised using piperidine amino acid as a raw material by chemical reaction.
Jan 18，2024 Drugs
Finerenone: Synthesis and Introduction
Finerenon, or BAY94- 8862, is a non-steroidal mineralocorticoid receptor (MR) antagonist approved by the USFDA in July 2021 and the EMA and the Japanese Ministry o
Jan 18，2024 Drugs
How is Anamorelin Monohydrochloride synthesised?
Anamorelin Monohydrochloride was synthesised starting from 2,2- Dimethylhydrazine by polymerisation of intermediate compounds.
Jan 18，2024 Drugs
Idebenone: A Multifaceted Compound for Antioxidant Activity and Mitochondrial Function
Idebenone acts as an electron carrier and enhances antioxidant defense mechanisms, protecting against mitochondrial dysfunction through multiple pathways. NQO1 activation is crucial for its activity.
Jan 18，2024 API
Glucose oxidase: a versatile enzyme with applications in food, textile, and biofuel industries
Glucose oxidase is a versatile enzyme used in food, textile, and biofuel industries, offering benefits like improved product quality, cost-effectiveness, and lower environmental impact.
Jan 18，2024 API
Avacopan: Synthesis and Introduction
Avacopan is synthesised using ethyl 3-(4-nitrophenyl)-3-oxo-propanoate as a raw material by chemical reaction.
Jan 18，2024 Drugs
An antibody drug conjugate: Enfortumab Vedotin
Enfortumab vedotin (EV) is an antibody?drug conjugate (ADC) consisting of a fully humanized monoclonal antibody targeting nectin-4 linked to the microtubule-disrupting agent monomethyl auristatin E (
Jan 17，2024 API