Sodium Stearyl Fumarate: An Essential Lubricant in Solid Dosage Forms with Safety Considerations
Sodium Stearyl Fumarate is a widely used lubricant in solid dosage forms, but caution is needed due to potential incompatibility issues and the need for proper handling.
Jan 26，2024 API
Dimethomorph: Pharmacokinetics, Mammalian Toxicity and Ecotoxicology
Dimethomorph is readily absorbed, rapidly metabolized, and efficiently eliminated from the body, showing low toxicity to mammals but adverse effects on liver and testes, with low ecotoxicity risks.
Jan 26，2024 API
Piroxicam: Pharmacokinetics, Mechanism of Action and Toxicology Studies
Piroxicam, a nonsteroidal anti-inflammatory drug with linear pharmacokinetics and a half-life of 30 to 60 hours, inhibits prostaglandin synthesis. High doses cause adverse pregnancy outcomes.
Jan 26，2024 API
Baloxavir Marboxil: A Cap-Dependent Endonuclease Inhibitor for the Treatment of Influenza
Baloxavir marboxil is a novel influenza treatment with single-dose administration, inhibiting viral gene transcription. Further research needed for efficacy and safety outside 48-hour window.
Jan 26，2024 API
Palladium-Catalyzed Reaction of 2-Hydroxy-2-methylpropiophenone with Aryl Bromides
Palladium-catalyzed reaction of 2-hydroxy-2-methylpropiophenone undergoes successive multiple arylation, with potential for selective synthesis using different aryl bromides and ligands.
Jan 26，2024 API
2-Methylbutane: Properties, Uses, and Safety Considerations in Industrial Applications
2-Methylbutane, a low-molecular-weight alkane derived from natural gas and crude oil, is versatile and safe for use as a solvent, building-block, and propellant in industrial processes and cosmetics.
Jan 26，2024 API
How to synthesize Zanubrutinib?
Zanubrutinib is a drug that was shown to effectively treat cancer of B cells without causing severe excessive side effects.
Jan 25，2024 Inhibitors
Mobocertinib: Synthesis and Introduction
Mobocertinib was approved as the first treatment for NSCLC with epidermal growth factor receptor (EGFR) exon 20 insertion mutations in patients whose disease has progressed after platinum-based chemot
Jan 25，2024 Inhibitors
Pafolacianine: Synthesis and Introduction
Pafolacianine is an imaging agent. Developed by On Target Laboratories, it has been approved for fluorescence-guided surgery in ovarian cancer.
Jan 25，2024 Drugs
Flame color of Copper sulfate and Principle of flame tests
Copper(II) sulfate, also known as copper sulphate, is an inorganic compound with the chemical formula CuSO4.
Jan 25，2024 Inorganic chemistry