An orally active HIF-PHD inhibitor: Roxadustat
Roxadustat is an orally administered small molecule drug that prevents the enzymatic degradation of HIF-1α by inhibiting the PHD enzymes.
Dec 25，2023 Inhibitors
Ursolic acid: Source; Biological activity and Mechanism of action
Ursolic acid is a pharmacologically active pentacyclic triterpenoid derived from medicinal plants, fruits and vegetables.
Dec 25，2023 Biochemical Engineering
Retinyl acetate: Introduction; Application and More
Retinyl acetate is derived from retinol. It can be used as a dietary supplement as a source of vitamin A.
Dec 25，2023 API
Synthetic pathway of Sofpironium Bromide
Sofpironium Bromide is prepared from two intermediates, α-hydroxyacid and pyrrolidine, by coupling and other reactions.
Dec 25，2023 Drugs
Clascoterone: Introduction and Synthesis
Clascoterone (cortexolone 17α-proprionate), a novel androgen receptor inhibitor, obtained its first approval by the USFDA in August 2020.
Dec 25，2023 Inhibitors
Abametapir：Introduction and Synthesis
Abametapir(5,5′-Dimethyl-2,2′-dipyridyl) is a topical drug used for the treatment of head lice infestation.It is prepared in two steps from 2-amino-5-methylpyridine.
Dec 25，2023 Pyridine Compound
Is BeCl2 a polar or a nonpolar compound?
BeCl2 is a nonpolar molecule, the linearly arranged chlorine's balance out around the central beryllium atom.
Dec 25，2023 Inorganic salts
What foods contain arginine in your daily diet?
Arginine, which plays a vital role in life, has many sources and can be taken from the daily diet.
Dec 25，2023 Amino Acids and Proteins
Is SiO2 Polar or Nonpolar?
SiO2 is a non-polar compound because of its linear and symmetrical shape.
Dec 25，2023 Inorganic chemistry
New study shows loratadine's efficacy in allergic rhinitis and urticaria
Loratadine is a long-acting antihistamine effective in treating allergic rhinitis and urticaria with predictable and dose-proportional pharmacokinetics, with minimal clinical interactions.
Dec 25，2023 API